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How to get fromRochester to Louisvilleby plane, bus (Greyhound, Flixbus, Amtrak), bus, train, car, or bus (Flixbus, Greyhound, Amtrak)

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There are 8 ways to get from Rochester to Louisville by plane, bus (Greyhound, Flixbus, Amtrak), bus, train, car, or bus (Flixbus, Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rochester to Louisville International Airport

    best
    1. Fly from Rochester (RST) to Louisville International Airport (SDF)plane plane RST - SDF
    6h 32m
    $92–590

  2. Bus

    1. Take the bus from Rochester to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Union Station to Louisville, KYbus bus
    16h 24m
    $133–182

  3. Bus, train

    1. Take the bus from Rochester to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    19h 21m
    $241–484

  4. Drive 639.9 mi

    1. Drive from Rochester to Louisvillecar car 639.9 mi
    10h 44m
    $117–169

  5. Bus to Minneapolis–Saint Paul International Airport, fly to Louisville International Airport

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Louisville International Airport (SDF)plane plane MSP - SDF
    5h 14m
    $161–703

  6. Fly Rochester to Blue Grass Airport, drive

    1. Fly from Rochester (RST) to Blue Grass Airport (LEX)plane plane RST - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    6h 51m
    $154–856

  7. Bus via Indianapolis

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from Madison to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    16h 55m
    $129–224

  8. Bus, train via Madison

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    18h 22m
    $162–309

Rochester to Louisville by bus and foot

Calendar7Weekly Services
Duration16h 24mAverage Duration
Ticket$133Cheapest Price
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Questions & Answers

Map of how to get from Rochester to Louisville.ExpandLaunch map view
  • Distance: 543.3 mi
  • Duration: 6h 32m

What companies run services between Rochester, MN, USA and Louisville, KY, USA?

United Airlines, Delta, and American Airlines fly from Rochester (RST) to Louisville International Airport (SDF) 4 times a day. Alternatively, you can take a bus from Rochester to Louisville, KY via Milwaukee, Milwaukee Intermodal Station, Chicago Bus Station, and Chicago Union Station in around 16h 24m.

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