There are 6 ways to get from Rochester to Florence by plane, bus, train (Amtrak), car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Florence Regional Airport
best- Fly from Rochester (ROC) to Florence Regional Airport (FLO)plane ROC - FLO
4h 18m$122–533Bus
- Take the bus from Rochester to New Yorkbus Adt N813 / ...
- Take the bus from New York, NY to Florence, SCbus Nyc
20h 14m$142–366Train (Amtrak)
- Take the train from Rochester to Ny Moynihan Train Hall At Penn Stationtrain Empire Service / ...
- Take the train from Ny Moynihan Train Hall At Penn Station to Florence Stationtrain Palmetto / ...
22h 46m$320–661Drive 752.9 mi
- Drive from Rochester to Florencecar 752.9 mi
14h 4m$138–199Fly to Myrtle Beach, bus
- Fly from Rochester (ROC) to Myrtle Beach (MYR)plane ROC - MYR
- Take the bus from Myrtle Beach to Florencebus
4h 52mBus via Washington
- Take the bus from Rochester Bus Stop to Ithacabus
- Take the bus from Ithaca to Washington Union Stationbus
- Take the bus from Washington Union Station to Raleigh Bus Stationbus
- Take the bus from Raleigh Bus Station to Florence Bus Stationbus
22h 33m$163–293
Rochester to Florence by train (Amtrak)
Questions & Answers
The cheapest way to get from Rochester to Florence is to drive which costs $130 - $200 and takes 14h 4m.
The fastest way to get from Rochester to Florence is to fly which takes 4h 18m and costs $120 - $550.
No, there is no direct bus from Rochester to Florence. However, there are services departing from Rochester and arriving at Florence, SC via 5 Av/W 42 St and New York, NY. The journey, including transfers, takes approximately 20h 14m.
No, there is no direct train from Rochester to Florence station. However, there are services departing from Rochester and arriving at Florence Station via Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 22h 46m.
The distance between Rochester and Florence is 637 miles. The road distance is 757.3 miles.
The best way to get from Rochester to Florence without a car is to bus which takes 20h 14m and costs $140 - $370.
It takes approximately 4h 18m to get from Rochester to Florence, including transfers.
Rochester to Florence bus services, operated by Trailways, depart from Rochester station.
Rochester to Florence train services, operated by Amtrak, depart from Rochester station.
The best way to get from Rochester to Florence is to fly which takes 4h 18m and costs $120 - $550. Alternatively, you can bus, which costs $140 - $370 and takes 20h 14m, you could also train, which costs $320 - $700 and takes 22h 46m.
What companies run services between Rochester, NY, USA and Florence, SC, USA?
American Airlines flies from Rochester (ROC) to Florence Regional Airport (FLO) twice daily. Alternatively, you can take a bus from Rochester to Florence, SC via New York, 5 Av/W 42 St, Centre St/Grand St, and New York, NY in around 20h 14m.
- Website
- aa.com
Flights from Rochester to Florence Regional Airport via Charlotte
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $95–500
Flights from Rochester to Florence Regional Airport via Reagan Washington, Charlotte
- Ave. Duration
- 8h 31m
- When
- Every day
- Estimated price
- $100–550
Flights from Rochester to Myrtle Beach via Reagan Washington
- Ave. Duration
- 4h 1m
- When
- Sunday
- Estimated price
- $80–430
Flights from Rochester to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 24m
- When
- Monday, Tuesday, Wednesday, Friday, and Sunday
- Estimated price
- $85–450
Flights from Rochester to Myrtle Beach via Philadelphia
- Ave. Duration
- 4h 30m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $85–450
- Website
- southwest.com
Flights from Rochester to Myrtle Beach via Baltimore
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $85–430
- Website
- flybreeze.com
Flights from Rochester to Myrtle Beach
- Ave. Duration
- 1h 57m
- When
- Thursday and Sunday
- Estimated price
- $180–700
- Website
- delta.com
Flights from Rochester to Myrtle Beach via Detroit
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $100–500
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Rochester to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 7h 5m
- Frequency
- 4 times a day
- Estimated price
- $120–250
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to Florence Station
- Ave. Duration
- 14h 41m
- Frequency
- Twice daily
- Estimated price
- $200–420
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Rochester to New York
- Ave. Duration
- 6h 15m
- Frequency
- Every 4 hours
- Estimated price
- $50–230
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $50–220
- Flexible
- $95–230
- Website
- example.com
Bus from Rochester to New York
- Ave. Duration
- 6h 15m
- Frequency
- 4 times a day
- Schedules at
- example.com
- Phone
- +1 646-630-7186
- [email protected]
- Website
- wandacoach.com
Bus from New York, NY to Florence, SC
- Ave. Duration
- 12h
- Frequency
- 3 times a day
- Estimated price
- $85–130
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Adult One Way
- $85–130
- Website
- example.com
Bus from Myrtle Beach to Florence
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Schedules at
- example.com
Bus from Raleigh Bus Station to Florence Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- Once daily
- Schedules at
- example.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Rochester Bus Stop to Ithaca
- Ave. Duration
- 2h 10m
- Frequency
- Twice daily
- Estimated price
- $14–24
- Schedules at
- flixbus.com
Bus from Ithaca to Washington Union Station
- Ave. Duration
- 10h
- Frequency
- 5 times a week
- Estimated price
- $85–140
- Schedules at
- flixbus.com
Bus from Washington Union Station to Raleigh Bus Station
- Ave. Duration
- 5h 5m
- Frequency
- Twice daily
- Estimated price
- $40–70
- Schedules at
- flixbus.com
- Website
- flixbus.com
Bus from Rochester Bus Stop to Ithaca
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Schedules at
- flixbus.com
Bus from Ithaca to Washington Union Station
- Ave. Duration
- 10h
- Frequency
- Twice a week
- Schedules at
- flixbus.com
Bus from Washington Union Station to Raleigh Bus Station
- Ave. Duration
- 5h 35m
- Frequency
- 3 times a day
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Washington Union Station to Raleigh Bus Station
- Ave. Duration
- 4h 40m
- Frequency
- Every 4 hours
- Estimated price
- $40–80
- Website
- https://www.greyhound.com/
Bus from Raleigh Bus Station to Florence Bus Station
- Ave. Duration
- 3h 4m
- Frequency
- Twice daily
- Estimated price
- $24–50
- Website
- https://www.greyhound.com/
- Website
- greyhound.com
Bus from Washington Union Station to Raleigh Bus Station
- Ave. Duration
- 5h 50m
- Frequency
- Every 4 hours
- Schedules at
- greyhound.com
Bus from Raleigh Bus Station to Florence Bus Station
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Schedules at
- greyhound.com
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More Questions & Answers
Rochester to Florence bus services, operated by Trailways, arrive at New York station.
Rochester to Florence train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Rochester to Florence is 757 miles. It takes approximately 14h 4m to drive from Rochester to Florence.
Book your Rochester to Florence train tickets online with Omio.
Book your Rochester to Florence bus tickets online with Omio.
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