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How to get fromRochester to Florida Keysby plane, bus (Flixbus, Greyhound), train, bus, or car

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There are 7 ways to get from Rochester to Florida Keys by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Rochester

    best
    1. Fly from Rochester (ROC) to Key West International Airport (EYW)plane plane ROC - EYW
    8h 45m
    $214–664

  2. Bus

    1. Take the bus from Rochester to Ithacabus bus 231
    2. Take the bus from Ithaca to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Miamibus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    42h 9m
    $294–533

  3. Train, bus via New York

    1. Take the train from Rochester to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    42h 52m
    $612–1,208

  4. Drive 1,546 mi

    1. Drive from Rochester to Florida Keyscar car 1,546 mi
    27h 38m
    $283–408

  5. Bus to Buffalo Niagara International Airport, fly

    1. Take the bus from Rochester Bus Stop to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW)plane plane BUF - EYW
    10h 5m
    $217–710

  6. Train, bus

    1. Take the train from Rochester to Cleveland Amtraktrain train
    2. Take the train from Cleveland Amtrak to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    2d 3h
    $672–1,429

  7. Bus, train

    1. Take the bus from Rochester to Buffalobus bus 308 / ...
    2. Take the bus from Buffalo, Ny to Pittsburgh, Pabus bus 530
    3. Take the train from Pittsburgh Amtrak Station to Miami Amtrak Stationtrain train
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    2d 5h
    $609–1,433

Rochester to Florida Keys by bus, taxi, and foot

Calendar4Weekly Services
Duration42h 9mAverage Duration
Ticket$294Cheapest Price
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Questions & Answers

Map of how to get from Rochester to Florida Keys.ExpandLaunch map view
  • Distance: 1,329.6 mi
  • Duration: 8h 45m

What companies run services between Rochester, NY, USA and Florida Keys, FL, USA?

Delta, American Airlines, and United Airlines fly from Rochester (ROC) to Key West International Airport (EYW) 4 times a day. Alternatively, you can take a bus from Rochester to Florida Keys via Ithaca, Washington Union Station, Miami, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 42h 9m.

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