There are 6 ways to get from Rochester to Key West by plane, bus (Flixbus, Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Rochester
best- Fly from Rochester (ROC) to Key West International Airport (EYW)plane ROC - EYW
5h 7m$148–633Bus to Buffalo Niagara International Airport, fly
cheapest- Take the bus from Rochester Bus Stop to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW)plane BUF - EYW
7h 9m$111–458Bus
- Take the bus from Rochester Bus Stop to Newark Penn Stationbus
- Take the bus from Newark Penn Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
39h 46m$286–435Train, bus via New York
- Take the train from Rochester to Albany-Rensselaer Amtrak Stationtrain
- Take the train from Albany-Rensselaer Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
44h 2m$929–1,592Drive 1,561.5 mi
- Drive from Rochester to Key Westcar 1,561.5 mi
28h 1m$285–412Train, bus
- Take the train from Rochester to Cleveland Amtraktrain
- Take the train from Cleveland Amtrak to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
2d 4h$1,079–1,772
Rochester to Key West by bus and foot
Comparing Your Travel Options
The cheapest way to get from Rochester to Key West is to bus and fly which costs $110 - $460 and takes 7h 9m.
The fastest way to get from Rochester to Key West is to fly which takes 5h 7m and costs $140 - $650.
No, there is no direct bus from Rochester to Key West. However, there are services departing from Rochester Bus Stop and arriving at N Roosevelt & 3rd Street via Newark Penn Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 39h 46m.
The distance between Rochester and Key West is 1318 miles. The road distance is 1570.6 miles.
The best way to get from Rochester to Key West without a car is to bus which takes 39h 46m and costs $280 - $440.
It takes approximately 5h 7m to get from Rochester to Key West, including transfers.
Rochester to Key West bus services, operated by Flixbus USA, depart from Rochester Bus Stop station.
The best way to get from Rochester to Key West is to fly which takes 5h 7m and costs $140 - $650. Alternatively, you can bus, which costs $280 - $440 and takes 39h 46m.
Rochester to Key West bus services, operated by Flixbus USA, arrive at Newark Penn Station.
Yes, the driving distance between Rochester to Key West is 1571 miles. It takes approximately 28h 1m to drive from Rochester to Key West.
What companies run services between Rochester, NY, USA and Key West, FL, USA?
Delta, American Airlines, and United Airlines fly from Rochester (ROC) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Rochester Bus Stop to N Roosevelt & 3rd Street via Newark Penn Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 39h 46m.
- Website
- aa.com
Flights from Rochester to Key West International Airport via Miami
- Ave. Duration
- 5h 43m
- When
- Saturday
- Estimated price
- $120–600
Flights from Rochester to Key West International Airport via Charlotte
- Ave. Duration
- 5h 59m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $120–600
Flights from Rochester to Key West International Airport via Reagan Washington
- Ave. Duration
- 6h 44m
- When
- Every day
- Estimated price
- $120–600
Flights from Buffalo Niagara International Airport to Key West International Airport via Reagan Washington
- Ave. Duration
- 5h 35m
- When
- Every day
- Estimated price
- $90–440
Flights from Buffalo Niagara International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 58m
- When
- Every day
- Estimated price
- $90–430
Flights from Buffalo Niagara International Airport to Key West International Airport via Miami
- Ave. Duration
- 8h 3m
- When
- Saturday
- Estimated price
- $90–440
- Website
- delta.com
Flights from Rochester to Key West International Airport via Atlanta
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $120–600
Flights from Buffalo Niagara International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 53m
- When
- Every day
- Estimated price
- $95–440
- Website
- united.com
Flights from Rochester to Key West International Airport via Washington Dulles
- Ave. Duration
- 6h 7m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $120–600
Flights from Buffalo Niagara International Airport to Key West International Airport via Washington Dulles
- Ave. Duration
- 6h 7m
- When
- Tuesday and Saturday
- Estimated price
- $90–440
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Rochester to Albany-Rensselaer Amtrak Station
- Ave. Duration
- 4h 2m
- Frequency
- 5 times a day
- Estimated price
- $120–200
- Website
- Amtrak
Train from Albany-Rensselaer Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 2h 31m
- Frequency
- Hourly
- Estimated price
- $75–120
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Station
- Ave. Duration
- 28h 29m
- Frequency
- Once daily
- Estimated price
- $750–1,200
- Website
- Amtrak
Train from Rochester to Cleveland Amtrak
- Ave. Duration
- 4h 24m
- Frequency
- Twice daily
- Estimated price
- $130–210
- Website
- Amtrak
Train from Cleveland Amtrak to Miami Amtrak Station
- Ave. Duration
- 40h 15m
- Frequency
- Once daily
- Estimated price
- $900–1,500
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Rochester to Albany-Rensselaer Amtrak Station
- Ave. Duration
- 4h 42m
- Frequency
- Once daily
- Estimated price
- $60–210
- Website
- VIA Rail
- Escape
- $60–150
- Business
- $95–200
- Business Plus
- $100–210
- Economy
- $65–160
- Economy Plus
- $75–170
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Rochester Bus Stop to Newark Penn Station
- Ave. Duration
- 6h 25m
- Frequency
- 5 times a day
- Estimated price
- $50–80
- Schedules at
- Flixbus USA
Bus from Newark Penn Station to Miami Airport Station
- Ave. Duration
- 25h 25m
- Frequency
- 4 times a week
- Estimated price
- $210–310
- Schedules at
- Flixbus USA
Bus from Rochester Bus Stop to Buffalo Niagara International Airport
- Ave. Duration
- 1h 10m
- Frequency
- Every 4 hours
- Estimated price
- $10–16
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Rochester Bus Stop to Newark Penn Station
- Ave. Duration
- 6h 40m
- Frequency
- Once daily
- Estimated price
- $55–90
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Website
- Greyhound
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- Key West Transit
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
There are 964+ hotels available in Key West.












