There are 7 ways to get from Rochester to Key West (Island) by plane, bus (Flixbus, Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Rochester
best- Fly from Rochester (ROC) to Key West International Airport (EYW)plane ROC - EYW
5h 31m$137–620Bus to Buffalo Niagara International Airport, fly
cheapest- Take the bus from Rochester Bus Stop to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Key West International Airport (EYW)plane BUF - EYW
7h 14m$105–464Bus
- Take the bus from Rochester to New Yorkbus
- Take the bus from New York to Washingtonbus
- Take the bus from Washington Union Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Key West Airportbus
39h 3m$293–618Train, bus via New York
- Take the train from Rochester to Albany-Rensselaer Amtrak Stationtrain
- Take the train from Albany-Rensselaer Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Key West Airportbus
42h 56m$472–1,137Drive 1,561.5 mi
- Drive from Rochester to Key Westcar 1,561.5 mi
28h 1m$285–412Train, bus
- Take the train from Rochester to Cleveland Amtraktrain
- Take the train from Cleveland Amtrak to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Key West Airportbus
2d 3h$531–1,188Bus, train
- Take the bus from Rochester to Buffalobus 308 / ...
- Take the bus from Buffalo, Ny to Pittsburgh, Pabus 530
- Take the train from Pittsburgh Amtrak Station to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Key West Airportbus
2d 6h$494–1,210
Rochester to Key West (Island) by bus
Comparing Your Travel Options
The cheapest way to get from Rochester to Key West (Island) is to bus and fly which costs $100 - $470 and takes 7h 14m.
The fastest way to get from Rochester to Key West (Island) is to fly which takes 5h 31m and costs $130 - $650.
No, there is no direct bus from Rochester to Key West (Island). However, there are services departing from Rochester and arriving at Key West Airport via New York, Washington Union Station and Miami Airport Station. The journey, including transfers, takes approximately 39h 3m.
The distance between Rochester and Key West (Island) is 1316 miles. The road distance is 1570.6 miles.
The best way to get from Rochester to Key West (Island) without a car is to bus which takes 39h 3m and costs $290 - $650.
It takes approximately 5h 31m to get from Rochester to Key West (Island), including transfers.
Rochester to Key West (Island) bus services, operated by Trailways, depart from Rochester station.
The best way to get from Rochester to Key West (Island) is to fly which takes 5h 31m and costs $130 - $650. Alternatively, you can bus, which costs $290 - $650 and takes 39h 3m.
Rochester to Key West (Island) bus services, operated by Trailways, arrive at New York station.
Yes, the driving distance between Rochester to Key West (Island) is 1571 miles. It takes approximately 28h 1m to drive from Rochester to Key West (Island).
What companies run services between Rochester, NY, USA and Key West (Island), FL, USA?
American Airlines, Delta, and United Airlines fly from Rochester (ROC) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Rochester to Key West Airport via New York, Washington, Washington Union Station, and Miami Airport Station in around 39h 3m.
- Website
- aa.com
Flights from Rochester to Key West International Airport via Charlotte
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $120–600
Flights from Rochester to Key West International Airport via Miami
- Ave. Duration
- 5h 52m
- When
- Saturday
- Estimated price
- $120–600
Flights from Rochester to Key West International Airport via Reagan Washington
- Ave. Duration
- 6h 24m
- When
- Every day
- Estimated price
- $120–600
Flights from Buffalo Niagara International Airport to Key West International Airport via Miami
- Ave. Duration
- 5h 36m
- When
- Saturday
- Estimated price
- $95–450
Flights from Buffalo Niagara International Airport to Key West International Airport via Reagan Washington
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $95–450
Flights from Buffalo Niagara International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 6h 24m
- When
- Every day
- Estimated price
- $95–450
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Rochester to Albany-Rensselaer Amtrak Station
- Ave. Duration
- 4h 2m
- Frequency
- 5 times a day
- Estimated price
- $55–140
- Website
- Amtrak
Train from Albany-Rensselaer Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 2h 31m
- Frequency
- Hourly
- Estimated price
- $35–85
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Hollywood Amtrak Station
- Ave. Duration
- 27h 51m
- Frequency
- Once daily
- Estimated price
- $350–800
- Website
- Amtrak
Train from Rochester to Cleveland Amtrak
- Ave. Duration
- 4h 24m
- Frequency
- Twice daily
- Estimated price
- $60–150
- Website
- Amtrak
Train from Cleveland Amtrak to Hollywood Amtrak Station
- Ave. Duration
- 39h 52m
- Frequency
- Once daily
- Estimated price
- $440–1,000
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Miami Amtrak Station
- Ave. Duration
- 36h 44m
- Frequency
- Once daily
- Estimated price
- $400–900
- Website
- Amtrak
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Rochester to New York
- Ave. Duration
- 6h 15m
- Frequency
- Every 4 hours
- Estimated price
- $50–230
- Website
- Trailways
- Schedules at
- Trailways
- Saver
- $50–220
- Flexible
- $95–230
Bus from Rochester to Buffalo
- Saver
- $19–45
- Flexible
- $39–45
Bus from Buffalo, Ny to Pittsburgh, Pa
- Saver
- $50–210
- Flexible
- $90–220
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
Book your Rochester to Key West (Island) bus tickets online with Omio.
There are 959+ hotels available in Key West (Island).







