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How to get fromRochester to La Crosseby plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or bus (Flixbus)

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There are 6 ways to get from Rochester to La Crosse by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Rochester

    best
    1. Fly from Rochester (ROC) to La Crosse (LSE)plane plane ROC - LSE
    5h 27m
    $136–593

  2. Bus to Buffalo Niagara International Airport, fly

    cheapest
    1. Take the bus from Rochester Bus Stop to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to La Crosse (LSE)plane plane BUF - LSE
    7h 49m
    $109–467

  3. Train (Amtrak)

    1. Take the train from Rochester to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    17h 42m
    $224–507

  4. Bus via Chicago

    1. Take the bus from Rochester Bus Stop to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to La Crossebus bus
    20h 50m
    $156–249

  5. Drive  880.2 mi

    1. Drive from Rochester to La Crossecar car 880.2 mi
    14h 54m
    $161–232

  6. Bus

    1. Take the bus from Rochester to Torontobus bus
    2. Take the bus from Toronto to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Appleton Transit Centerbus bus
    4. Take the bus from Appleton Valley Transit to La Crosse Grand River Stationbus bus
    28h 50m
    $170–313

Rochester to La Crosse by train (Amtrak)

Calendar14Weekly Trains
Duration17h 42mAverage Duration
Ticket$224Cheapest Price
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Comparing Your Travel Options

Map of how to get from Rochester to La Crosse.ExpandLaunch map view
  • Distance: 694.3 mi
  • Duration: 5h 27m

What companies run services between Rochester, NY, USA and La Crosse, WI, USA?

American Airlines and United Airlines fly from Rochester (ROC) to La Crosse (LSE) every 4 hours. Alternatively, you can take a train from Rochester to La Crosse Amtrak Station via Chicago Union Station in around 17h 42m.

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