There are 7 ways to get from Rochester to Palo Alto by plane, bus (Greyhound), train, subway, car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Rochester to San Francisco International Airport
best- Fly from Rochester (ROC) to San Francisco International Airport (SFO)plane ROC - SFO
8h 55m$210–788Bus to Buffalo Niagara International Airport, fly to Norman Y. Mineta San José International Airport
cheapest- Take the bus from Rochester Bus Stop to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Norman Y. Mineta San José International Airport (SJC)plane BUF - SJC
10h 39m$197–774Bus
- Take the bus from Rochester Bus Stop to Cleveland Bus Stationbus
- Take the bus from Cleveland Bus Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Denver Union Stationbus
- Take the bus from Denver Union Station to Sparks Transit Centerbus
- Take the bus from Sparks Transit Center to San Francisco Bus Stationbus
- Take the bus from Salesforce Transit Center- Bay 37 to Clarke Ave & O'Connor St-Ravenswood Shopping Ctrbus Epx
2d 19h$524–808Train, BART
- Take the train from Rochester to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Richmondtrain
- Take the subway from Richmond to Millbraesubway
2d 19h$1,642–2,621Drive 2,727.7 mi
- Drive from Rochester to Palo Altocar 2,727.7 mi
43h 38m$482–697Fly Rochester to Norman Y. Mineta San José International Airport
- Fly from Rochester (ROC) to Norman Y. Mineta San José International Airport (SJC)plane ROC - SJC
9h 4m$284–1,129Fly Rochester to Oakland International Airport, train
- Fly from Rochester (ROC) to Oakland International Airport (OAK)plane ROC - OAK
- Take the train from Oakland Coliseum/Airport Amtrak to Santa Clara Amtraktrain
10h 37m$283–1,064
Rochester to Palo Alto by bus
Comparing Your Travel Options
The cheapest way to get from Rochester to Palo Alto is to bus and fly which costs $190 - $800 and takes 10h 39m.
The fastest way to get from Rochester to Palo Alto is to fly which takes 8h 55m and costs $210 - $800.
No, there is no direct bus from Rochester to Palo Alto. However, there are services departing from Rochester Bus Stop and arriving at Clarke Ave & O'Connor St-Ravenswood Shopping Ctr via Cleveland Bus Station, Chicago Bus Station, Denver Union Station, Sparks Transit Center and Salesforce Transit Center- Bay 37. The journey, including transfers, takes approximately 2 days 19h.
No, there is no direct train from Rochester to Palo Alto. However, there are services departing from Rochester and arriving at California Avenue Caltrain Southbound via Chicago Union Station, Richmond and Millbrae Caltrain Southbound. The journey, including transfers, takes approximately 2 days 19h.
The distance between Rochester and Palo Alto is 2395 miles. The road distance is 2743.6 miles.
The best way to get from Rochester to Palo Alto without a car is to bus which takes 2 days 19h and costs $500 - $850.
It takes approximately 8h 55m to get from Rochester to Palo Alto, including transfers.
Rochester to Palo Alto bus services, operated by Greyhound USA, depart from Rochester Bus Stop station.
Rochester to Palo Alto train services, operated by Amtrak, depart from Rochester station.
The best way to get from Rochester to Palo Alto is to fly which takes 8h 55m and costs $210 - $800. Alternatively, you can bus, which costs $500 - $850 and takes 2 days 19h.
What companies run services between Rochester, NY, USA and Palo Alto, CA, USA?
Delta, Southwest Airlines, and two other airlines fly from Rochester (ROC) to San Francisco International Airport (SFO) hourly. Alternatively, you can take a bus from Rochester Bus Stop to Clarke Ave & O'Connor St-Ravenswood Shopping Ctr via Cleveland Bus Station, Chicago Bus Station, Denver Union Station, Sparks Transit Center, San Francisco Bus Station, and Salesforce Transit Center- Bay 37 in around 2d 19h.
- Website
- southwest.com
Flights from Rochester to San Francisco International Airport via Chicago Midway
- Ave. Duration
- 8h 33m
- When
- Every day
- Estimated price
- $180–750
Flights from Rochester to San Francisco International Airport via Baltimore
- Ave. Duration
- 10h 55m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $200–800
Flights from Rochester to Norman Y. Mineta San José International Airport via Chicago Midway
- Ave. Duration
- 7h 57m
- When
- Every day
- Estimated price
- $260–1,100
Flights from Rochester to Norman Y. Mineta San José International Airport via Orlando
- Ave. Duration
- 9h 50m
- When
- Saturday
- Estimated price
- $360–1,400
Flights from Rochester to Norman Y. Mineta San José International Airport via Baltimore
- Ave. Duration
- 11h 5m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $290–1,200
Flights from Rochester to Oakland International Airport via Chicago Midway
- Ave. Duration
- 8h 5m
- When
- Every day
- Estimated price
- $240–1,000
Flights from Rochester to Oakland International Airport via Chicago Midway, Denver
- Ave. Duration
- 10h 50m
- When
- Thursday
- Estimated price
- $240–1,000
Flights from Buffalo Niagara International Airport to Norman Y. Mineta San José International Airport via Chicago Midway
- Ave. Duration
- 8h 1m
- When
- Every day
- Estimated price
- $180–750
Flights from Buffalo Niagara International Airport to Norman Y. Mineta San José International Airport via Phoenix
- Ave. Duration
- 8h
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $200–800
Flights from Buffalo Niagara International Airport to Norman Y. Mineta San José International Airport via Denver
- Ave. Duration
- 8h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–750
Flights from Buffalo Niagara International Airport to Norman Y. Mineta San José International Airport via Las Vegas
- Ave. Duration
- 8h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $180–800
- Website
- united.com
Flights from Rochester to San Francisco International Airport via Washington Dulles
- Ave. Duration
- 9h 13m
- When
- Every day
- Estimated price
- $200–800
Flights from Rochester to San Francisco International Airport via Chicago O'Hare
- Ave. Duration
- 8h 44m
- When
- Every day
- Estimated price
- $180–750
Flights from Rochester to Norman Y. Mineta San José International Airport via Chicago O'Hare
- Ave. Duration
- 8h 38m
- When
- Every day
- Estimated price
- $260–1,100
Flights from Buffalo Niagara International Airport to Norman Y. Mineta San José International Airport via Denver
- Ave. Duration
- 7h 28m
- When
- Every day
- Estimated price
- $180–750
Flights from Buffalo Niagara International Airport to Norman Y. Mineta San José International Airport via Chicago O'Hare
- Ave. Duration
- 8h 31m
- When
- Every day
- Estimated price
- $180–750
- Website
- delta.com
Flights from Rochester to San Francisco International Airport via Detroit
- Ave. Duration
- 8h 7m
- When
- Every day
- Estimated price
- $180–750
Flights from Rochester to Norman Y. Mineta San José International Airport via Atlanta
- Ave. Duration
- 9h 20m
- When
- Every day
- Estimated price
- $300–1,200
Flights from Rochester to Oakland International Airport via Detroit, Salt Lake City
- Ave. Duration
- 11h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $240–1,000
- Website
- aa.com
Flights from Rochester to San Francisco International Airport via Chicago O'Hare
- Ave. Duration
- 9h 31m
- When
- Every day
- Estimated price
- $180–750
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Rochester to Chicago Union Station
- Ave. Duration
- 11h 43m
- Frequency
- Twice daily
- Estimated price
- $320–500
- Website
- Amtrak
Train from Chicago Union Station to Richmond
- Ave. Duration
- 2d 4h
- Frequency
- Once daily
- Estimated price
- $1,300–2,100
- Website
- Amtrak
Train from Oakland Coliseum/Airport Amtrak to Santa Clara Amtrak
- Ave. Duration
- 51 min
- Frequency
- Every 4 hours
- Estimated price
- $20–35
- Website
- Amtrak
- Phone
- +1-510-464-6000
- Website
- BART
Subway from Richmond to Millbrae
- Ave. Duration
- 1h 17m
- Frequency
- Every 30 minutes
- Estimated price
- $12–16
- Website
- BART
- Adult Single Ride
- $12–16
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Rochester Bus Stop to Cleveland Bus Station
- Ave. Duration
- 5h 5m
- Frequency
- Twice daily
- Estimated price
- $50–75
- Website
- Greyhound
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- 4 times a day
- Estimated price
- $60–95
- Website
- Greyhound
Bus from Chicago Bus Station to Denver Union Station
- Ave. Duration
- 21h 35m
- Frequency
- Twice daily
- Estimated price
- $180–280
- Website
- Greyhound
Bus from Denver Union Station to Sparks Transit Center
- Ave. Duration
- 20h 45m
- Frequency
- Twice daily
- Estimated price
- $190–290
- Website
- Greyhound
Bus from Sparks Transit Center to San Francisco Bus Station
- Ave. Duration
- 6h 20m
- Frequency
- 4 times a day
- Estimated price
- $40–65
- Website
- Greyhound
- Phone
- 1-800-660-4287
- [email protected]
- Website
- SamTrans Homepage
Bus from Salesforce Transit Center- Bay 37 to Clarke Ave & O'Connor St-Ravenswood Shopping Ctr
- Ave. Duration
- 1h 36m
- Frequency
- 4 times a day
- Estimated price
- $3
- Website
- SamTrans Homepage
- Schedules at
- SamTrans Schedules
- Single Fare
- $3
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Rochester Bus Stop to Buffalo Niagara International Airport
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- $10–16
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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Booking & Getting There
Rochester to Palo Alto bus services, operated by Greyhound USA, arrive at Cleveland Bus Station.
Palo Alto is 3h behind Rochester. It is currently 5:42 PM in Rochester and 2:42 PM in Palo Alto.
Rochester to Palo Alto train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Rochester to Palo Alto is 2744 miles. It takes approximately 43h 38m to drive from Rochester to Palo Alto.
There are 487+ hotels available in Palo Alto.









