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How to get fromRochester to Winston-Salemby plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

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There are 7 ways to get from Rochester to Winston-Salem by plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Piedmont Triad International Airport

    best
    1. Fly from Rochester (ROC) to Piedmont Triad International Airport (GSO)plane plane ROC - GSO
    5h 4m
    $166–843

  2. Bus

    cheapest
    1. Take the bus from Rochester Bus Stop to Buffalobus bus
    2. Take the bus from Buffalo, NY to Robert K Pfaff Transit Center - Akronbus bus
    3. Take the bus from Robert K Pfaff Transit Center - Akron to Charleston, WVbus bus
    4. Take the bus from Charleston Bus Station to Winston Salem(Trans Center)bus bus
    17h 55m
    $89–228

  3. Train (Amtrak)

    1. Take the train from Rochester to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to High Pointtrain train Crescent / ...
    20h 37m
    $241–533

  4. Drive  623.6 mi

    1. Drive from Rochester to Winston-Salemcar car 623.6 mi
    12h 10m
    $114–165

  5. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Rochester (ROC) to Charlotte Douglas International Airport (CLT)plane plane ROC - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    5h 22m
    $138–716

  6. Fly to Raleigh-Durham International Airport, bus

    1. Fly from Rochester (ROC) to Raleigh-Durham International Airport (RDU)plane plane ROC - RDU
    2. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    6h 5m
    $155–951

  7. Bus via New York

    1. Take the bus from Rochester Bus Stop to New York Midtownbus bus FlixBus 2685 / ...
    2. Take the bus from New York, NY to Winston-Salem, NCbus bus Nyc
    18h 37m
    $140–204

Rochester to Winston-Salem by bus

Calendar7Weekly Buses
Duration17h 55mAverage Duration
Ticket$89Cheapest Price
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Questions & Answers

Map of how to get from Rochester to Winston-Salem.ExpandLaunch map view
  • Distance: 527.3 mi
  • Duration: 5h 4m

What companies run services between Rochester, NY, USA and Winston-Salem, NC, USA?

United Airlines, Delta, and American Airlines fly from Rochester (ROC) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a bus from Rochester Bus Stop to Winston Salem(Trans Center) via Buffalo, Buffalo, NY, Robert K Pfaff Transit Center - Akron, and Charleston Bus Station in around 17h 55m.

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