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How to get fromRome to Lancasterby train (Amtrak), bus (Greyhound), or car

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There are 4 ways to get from Rome to Lancaster by train (Amtrak), bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Rome Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Empire Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Elizabethtown Amtrak Stationtrain train Keystone Service / ...
    11h 1m
    $126–280
  2. Drive 270.7 mi

    cheapest
    1. Drive from Rome to Lancastercar car 270.7 mi
    5h 53m
    $50–72
  3. Bus

    1. Take the bus from Rome W Liberty St to Syracuse Centrobus bus
    2. Take the bus from Syracuse Bus Station to Scranton Bus Stationbus bus
    3. Take the bus from Scranton, Pa to Harrisburg, Pabus bus 771
    13h 16m
    $53–139
  4. Train via New York

    1. Take the train from Rome to New York Penn Stationtrain train VIA Rail
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Elizabethtown Amtrak Stationtrain train Keystone Service / ...
    11h 44m
    $118–339

Rome to Lancaster by train and bus (Amtrak)

Calendar21Weekly Services
Duration11h 1mAverage Duration
Ticket$126Cheapest Price
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Questions & Answers

What companies run services between Rome, Oneida County, NY, USA and Lancaster, PA, USA?

You can take a train from Rome Amtrak Station to W. Chestnut & Water St. via Ny Moynihan Train Hall At Penn Station, Elizabethtown Amtrak Station, and AMTRAK ETown in around 11h 1m. Alternatively, you can take a bus from Rome W Liberty St to W. Chestnut & Water St. via Syracuse Centro, B8, Syracuse Bus Station, Scranton, Pa, Harrisburg, Pa, Harrisburg, Elizabethtown Amtrak Station, and AMTRAK ETown in around 13h 16m.

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