There are 6 ways to get from Rome to Cape Girardeau by plane, taxi, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Williamson County Regional Airport, taxi
best- Fly from Fiumicino International Airport (FCO) to Williamson County Regional Airport (MWA)plane FCO - MWA
- Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi
20h 30m$454–1,116Fly to Decatur Airport, bus
cheapest- Fly from Fiumicino International Airport (FCO) to Decatur Airport (DEC)plane FCO - DEC
- Take the bus from Decatur Downtown Transportation Center to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Cape Girardeaubus
22h 24m$376–997Fly to Barkley Regional Airport, taxi
- Fly from Fiumicino International Airport (FCO) to Barkley Regional Airport (PAH)plane FCO - PAH
- Take the taxi from Barkley Regional Airport (PAH) to Cape Girardeautaxi
19h 27m$454–1,376Fly to Lambert–St. Louis International Airport, bus
- Fly from Fiumicino International Airport (FCO) to Lambert–St. Louis International Airport (STL)plane FCO - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
19h 36m$634–1,348Fly to Cape Girardeau Municipal Airport
- Fly from Fiumicino International Airport (FCO) to Cape Girardeau Municipal Airport (CGI)plane FCO - CGI
17h 19m$427–1,234Fly to Abraham Lincoln Capital Airport, train, bus
- Fly from Fiumicino International Airport (FCO) to Abraham Lincoln Capital Airport (SPI)plane FCO - SPI
- Take the train from Springfield to St. Louistrain
- Take the bus from St Louis Bus Station to Cape Girardeaubus
24h 51m$404–1,046
Fiumicino International Airport (FCO) to Williamson County Regional Airport (MWA) flights
Comparing Your Travel Options
The cheapest way to get from Rome to Cape Girardeau is to fly and bus which costs $370 - $1,000 and takes 22h 24m.
The fastest way to get from Rome to Cape Girardeau is to fly which takes 17h 19m and costs $420 - $1,300.
The distance between Rome and Cape Girardeau is 5148 miles.
It takes approximately 20h 30m to get from Rome to Cape Girardeau, including transfers.
Cape Girardeau is 6h behind Rome. It is currently 6:35 AM in Rome and 12:35 AM in Cape Girardeau.
There are 20+ hotels available in Cape Girardeau.
What companies run services between Rome, Italy and Cape Girardeau, MO, USA?
Ethiopian Airlines and Corporate Flight Management Inc fly from Fiumicino International Airport (FCO) to Cape Girardeau Municipal Airport (CGI) 4 times a week.
- Website
- aa.com
Flights from Fiumicino International Airport to Williamson County Regional Airport via Chicago O'Hare
- Ave. Duration
- 20h 39m
- When
- Every day
- Estimated price
- $290–1,100
Flights from Fiumicino International Airport to Williamson County Regional Airport via Frankfurt, Chicago O'Hare
- Ave. Duration
- 16h 48m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $320–1,200
Flights from Fiumicino International Airport to Williamson County Regional Airport via Munich, Chicago O'Hare
- Ave. Duration
- 17h 38m
- When
- Every day
- Estimated price
- $320–1,200
Flights from Fiumicino International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 13h 26m
- When
- Tuesday
- Estimated price
- $370–1,400
Flights from Fiumicino International Airport to Lambert–St. Louis International Airport via Philadelphia
- Ave. Duration
- 14h 25m
- When
- Saturday
- Estimated price
- $380–1,400
Flights from Fiumicino International Airport to Lambert–St. Louis International Airport via Charlotte
- Ave. Duration
- 16h 34m
- When
- Tuesday
- Estimated price
- $400–1,500
Flights from Fiumicino International Airport to Abraham Lincoln Capital Airport via Chicago O'Hare
- Ave. Duration
- 19h 26m
- When
- Every day
- Estimated price
- $270–1,100
Flights from Fiumicino International Airport to Abraham Lincoln Capital Airport via Frankfurt, Chicago O'Hare
- Ave. Duration
- 16h 39m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $310–1,100
Flights from Fiumicino International Airport to Abraham Lincoln Capital Airport via Munich, Chicago O'Hare
- Ave. Duration
- 17h 29m
- When
- Every day
- Estimated price
- $310–1,100
- Website
- united.com
Flights from Fiumicino International Airport to Barkley Regional Airport via Chicago O'Hare
- Ave. Duration
- 15h 26m
- When
- Monday, Wednesday, Thursday, and Saturday
- Estimated price
- $400–1,200
Flights from Fiumicino International Airport to Barkley Regional Airport via Frankfurt, Chicago O'Hare
- Ave. Duration
- 30h 11m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $310–1,200
Flights from Fiumicino International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 13h 12m
- When
- Sunday
- Estimated price
- $370–1,400
Flights from Fiumicino International Airport to Lambert–St. Louis International Airport via Washington Dulles
- Ave. Duration
- 14h 30m
- When
- Every day
- Estimated price
- $380–1,400
Flights from Fiumicino International Airport to Decatur Airport via Chicago O'Hare
- Ave. Duration
- 14h 16m
- When
- Every day
- Estimated price
- $270–1,000
Flights from Fiumicino International Airport to Decatur Airport via Munich, Chicago O'Hare
- Ave. Duration
- 16h 7m
- When
- Every day
- Estimated price
- $280–1,100
Flights from Fiumicino International Airport to Decatur Airport via Frankfurt, Chicago O'Hare
- Ave. Duration
- 16h 50m
- When
- Every day
- Estimated price
- $300–1,100
- Website
- delta.com
Flights from Fiumicino International Airport to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 13h 19m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $370–1,400
Flights from Fiumicino International Airport to Lambert–St. Louis International Airport via Minneapolis
- Ave. Duration
- 15h
- When
- Wednesday, Friday, and Sunday
- Estimated price
- $390–1,500
- Website
- contouraviation.com
Flights from Fiumicino International Airport to Cape Girardeau Municipal Airport via Chicago O'Hare
- Ave. Duration
- 14h 35m
- When
- Monday, Wednesday, Thursday, and Saturday
- Estimated price
- $400–1,200
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Springfield to St. Louis
- Ave. Duration
- 1h 48m
- Frequency
- 5 times a day
- Estimated price
- $50–85
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $20–30
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $20–30
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $20–30
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Decatur Downtown Transportation Center to St Louis Bus Station
- Ave. Duration
- 2h 30m
- Frequency
- 5 times a week
- Estimated price
- $21–35
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Italy Travel Guides
Read the travel guide
Need to know: Greyhound
Read the travel guide









