There are 5 ways to get from Rome to Guayaquil by plane, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Fiumicino International Airport to José Joaquín De Olmedo International Airport
best- Fly from Fiumicino International Airport (FCO) to José Joaquín De Olmedo International Airport (GYE)plane FCO - GYE
17h 52m$374–1,106Fly Fiumicino International Airport to Eloy Alfaro International Airport, bus
cheapest- Fly from Fiumicino International Airport (FCO) to Eloy Alfaro International Airport (MEC)plane FCO - MEC
- Take the bus from Manta to Terminal Terrestre de Guayaquilbus
25h 1m$361–1,221Train to Florence Peretola Airport, fly to José Joaquín De Olmedo International Airport
- Take the train from Roma Termini to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to José Joaquín De Olmedo International Airport (GYE)plane FLR - GYE
20h 55m$424–1,469Train to Naples Airport, fly to José Joaquín De Olmedo International Airport
- Take the train from Roma Termini to Napoli Afragolatrain
- Fly from Naples Airport (NAP) to José Joaquín De Olmedo International Airport (GYE)plane NAP - GYE
23h 38m$417–1,457Fly Roma Ciampino Airport to José Joaquín De Olmedo International Airport
- Fly from Roma Ciampino Airport (CIA) to José Joaquín De Olmedo International Airport (GYE)plane CIA - GYE
24h 13m$502–1,512
Fiumicino International Airport (FCO) to José Joaquín De Olmedo International Airport (GYE) flights
Comparing Your Travel Options
The cheapest way to get from Rome to Guayaquil is to fly which costs $370 - $1,200 and takes 17h 52m.
The fastest way to get from Rome to Guayaquil is to fly which takes 17h 52m and costs $370 - $1,200.
The distance between Rome and Guayaquil is 10375 km.
It takes approximately 17h 52m to get from Rome to Guayaquil, including transfers.
Guayaquil is 6h behind Rome. It is currently 12:37 AM in Rome and 6:37 PM in Guayaquil.
There are 417+ hotels available in Guayaquil.
What companies run services between Rome, Italy and Guayaquil, Ecuador?
American Airlines, Iberia, and three other airlines fly from Fiumicino International Airport (FCO) to José Joaquín De Olmedo International Airport (GYE) 3 times a day.
- Website
- iberia.com
Flights from Fiumicino International Airport to José Joaquín De Olmedo International Airport via Madrid
- Ave. Duration
- 16h 17m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- $360–1,200
Flights from Florence Peretola Airport to José Joaquín De Olmedo International Airport via Madrid
- Ave. Duration
- 17h 55m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- $460–1,500
Flights from Florence Peretola Airport to José Joaquín De Olmedo International Airport via Madrid, Quito
- Ave. Duration
- 17h 45m
- When
- Thursday
- Estimated price
- $460–1,500
Flights from Naples Airport to José Joaquín De Olmedo International Airport via Madrid
- Ave. Duration
- 33h 40m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $420–1,400
Flights from Naples Airport to José Joaquín De Olmedo International Airport via Madrid, Quito
- Ave. Duration
- 33h 30m
- When
- Tuesday and Wednesday
- Estimated price
- $420–1,400
Flights from Roma Ciampino Airport to José Joaquín De Olmedo International Airport via Marseille, Madrid
- Ave. Duration
- 31h 35m
- When
- Monday
- Estimated price
- $490–1,600
- Website
- aireuropa.com
Flights from Fiumicino International Airport to José Joaquín De Olmedo International Airport via Madrid
- Ave. Duration
- 17h 20m
- When
- Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- $400–1,200
Flights from Florence Peretola Airport to José Joaquín De Olmedo International Airport via Madrid
- Ave. Duration
- 16h 50m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $500–1,500
Flights from Naples Airport to José Joaquín De Olmedo International Airport via Madrid
- Ave. Duration
- 19h 20m
- When
- Thursday
- Estimated price
- $470–1,300
Flights from Roma Ciampino Airport to José Joaquín De Olmedo International Airport via Cagliari, Madrid
- Ave. Duration
- 25h 15m
- When
- Sunday
- Estimated price
- $550–1,500
Flights from Roma Ciampino Airport to José Joaquín De Olmedo International Airport via Marseille, Madrid
- Ave. Duration
- 21h 45m
- When
- Sunday
- Estimated price
- $500–1,500
- Website
- avianca.com
Flights from Florence Peretola Airport to José Joaquín De Olmedo International Airport via Paris Charles de Gaulle, Bogota
- Ave. Duration
- 19h 40m
- When
- Every day
- Estimated price
- $390–1,400
Flights from Florence Peretola Airport to José Joaquín De Olmedo International Airport via Barcelona, Bogota
- Ave. Duration
- 19h 45m
- When
- Monday to Saturday
- Estimated price
- $600–1,800
Flights from Naples Airport to José Joaquín De Olmedo International Airport via New York JFK
- Ave. Duration
- 27h 45m
- When
- Every day
- Estimated price
- $390–1,400
Flights from Naples Airport to José Joaquín De Olmedo International Airport via Barcelona, Bogota
- Ave. Duration
- 19h 45m
- When
- Tuesday, Friday, and Saturday
- Estimated price
- $550–1,600
Flights from Fiumicino International Airport to Eloy Alfaro International Airport via Montreal, Quito
- Ave. Duration
- 23h 40m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- $350–1,200
Flights from Roma Ciampino Airport to José Joaquín De Olmedo International Airport via Cagliari, Madrid, Bogota
- Ave. Duration
- 26h 55m
- When
- Sunday
- Estimated price
- $600–1,900
- Website
- latam.com
Flights from Fiumicino International Airport to José Joaquín De Olmedo International Airport via Madrid
- Ave. Duration
- 16h 17m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- $360–1,200
Flights from Fiumicino International Airport to Eloy Alfaro International Airport via Madrid, Quito
- Ave. Duration
- 18h 52m
- When
- Wednesday and Thursday
- Estimated price
- $370–1,200
Flights from Roma Ciampino Airport to José Joaquín De Olmedo International Airport via Marseille, Madrid
- Ave. Duration
- 31h 35m
- When
- Monday
- Estimated price
- $490–1,600
- Website
- aa.com
Flights from Fiumicino International Airport to José Joaquín De Olmedo International Airport via Miami
- Ave. Duration
- 17h 43m
- When
- Every day
- Estimated price
- $330–1,200
- Website
- airfrance.com
Flights from Florence Peretola Airport to José Joaquín De Olmedo International Airport via Paris Charles de Gaulle, Panama City
- Ave. Duration
- 17h 25m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $400–1,400
- Website
- delta.com
Flights from Naples Airport to José Joaquín De Olmedo International Airport via New York JFK
- Ave. Duration
- 27h 52m
- When
- Every day
- Estimated price
- $390–1,400
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 42m
- Frequency
- Hourly
- Estimated price
- $40–70
- Website
- Trenitalia Frecce
Train from Roma Termini to Napoli Afragola
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- $30–55
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 51m
- Frequency
- 4 times a day
- Estimated price
- $35–60
- Website
- Italo Treno
Train from Roma Termini to Napoli Afragola
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- $28–45
- Website
- Italo Treno
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 40m
- Frequency
- 5 times a day
- Estimated price
- $35–50
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 45m
- Frequency
- 6 times a week
- Estimated price
- $30–60
- Website
- Trenitalia Intercity
Train from Roma Termini to Napoli Afragola
- Ave. Duration
- 2h 53m
- Frequency
- Once a week
- Estimated price
- $25–50
- Website
- Trenitalia Intercity
- [email protected]
- Website
- Cooperativa Reina del Camino
Bus from Manta to Terminal Terrestre de Guayaquil
- Ave. Duration
- 3h 15m
- Frequency
- Hourly
- Estimated price
- $7–15
- Website
- Cooperativa Reina del Camino
Want to know more about travelling around Ecuador
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
Getting to Rome from the airport
Read the travel guide

















