Rome2Rio

How to get fromRome to Knoxvilleby plane, car, or shuttle

Find Transport to Knoxville

See all options

There are 7 ways to get from Rome to Knoxville by plane, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport

    best
    1. Fly from Fiumicino International Airport (FCO) to Mcghee Tyson Airport (TYS)plane plane FCO - TYS
    15h 9m
    $709–2,576

  2. Fly to Chattanooga Metropolitan Airport, drive

    cheapest
    1. Fly from Fiumicino International Airport (FCO) to Chattanooga Metropolitan Airport (CHA)plane plane FCO - CHA
    2. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar car
    17h
    $281–982

  3. Fly to Asheville Regional Airport, drive

    1. Fly from Fiumicino International Airport (FCO) to Asheville Regional Airport (AVL)plane plane FCO - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    17h 20m
    $314–936

  4. Fly to Hartsfield-Jackson Atlanta International Airport, drive

    1. Fly from Fiumicino International Airport (FCO) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane FCO - ATL
    2. Drive from Atlanta-Airport-ATL to Knoxvillecar car
    16h 43m
    $489–1,361

  5. Fly to Greenville–Spartanburg International Airport, drive

    1. Fly from Fiumicino International Airport (FCO) to Greenville–Spartanburg International Airport (GSP)plane plane FCO - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Knoxvillecar car
    18h 15m
    $443–1,551

  6. Fly to Blue Grass Airport, drive

    1. Fly from Fiumicino International Airport (FCO) to Blue Grass Airport (LEX)plane plane FCO - LEX
    2. Drive from Lexington-Airport-LEX to Knoxvillecar car
    18h 43m
    $344–951

  7. Fly to Tri-Cities Regional Tn/Va Airport, shuttle, drive

    1. Fly from Fiumicino International Airport (FCO) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane FCO - TRI
    2. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    3. Drive from Hot Springs to Knoxvillecar car
    21h 27m
    $480–1,179

Fiumicino International Airport (FCO) to Mcghee Tyson Airport (TYS) flights

Calendar56Weekly Planes
Duration14h 10mAverage Duration
Ticket$684Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Rome to Knoxville.ExpandLaunch map view
  • Distance: 4,944 mi
  • Duration: 15h 9m

What companies run services between Rome, Italy and Knoxville, TN, USA?

Ethiopian Airlines, United Airlines, and two other airlines fly from Fiumicino International Airport (FCO) to Mcghee Tyson Airport (TYS) every 4 hours.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides