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How to get fromRome to Knoxvilleby plane, car, or shuttle

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There are 7 ways to get from Rome to Knoxville by plane, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport

    best
    1. Fly from Fiumicino International Airport (FCO) to Mcghee Tyson Airport (TYS)plane plane FCO - TYS
    15h 24m
    $659–2,277

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Fiumicino International Airport (FCO) to Asheville Regional Airport (AVL)plane plane FCO - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    17h 18m
    $316–1,142

  3. Fly to Chattanooga Metropolitan Airport, drive

    1. Fly from Fiumicino International Airport (FCO) to Chattanooga Metropolitan Airport (CHA)plane plane FCO - CHA
    2. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar car
    17h 10m
    $322–1,135

  4. Fly to Hartsfield-Jackson Atlanta International Airport, drive

    1. Fly from Fiumicino International Airport (FCO) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane FCO - ATL
    2. Drive from Atlanta-Airport-ATL to Knoxvillecar car
    16h 43m
    $489–1,367

  5. Fly to Greenville–Spartanburg International Airport, drive

    1. Fly from Fiumicino International Airport (FCO) to Greenville–Spartanburg International Airport (GSP)plane plane FCO - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Knoxvillecar car
    19h 3m
    $484–1,657

  6. Fly to Covington, drive

    1. Fly from Fiumicino International Airport (FCO) to Covington (CVG)plane plane FCO - CVG
    2. Drive from Covington (CVG) to Knoxvillecar car
    19h 42m
    $509–1,772

  7. Fly to Tri-Cities Regional Tn/Va Airport, shuttle, drive

    1. Fly from Fiumicino International Airport (FCO) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane FCO - TRI
    2. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    3. Drive from Hot Springs to Knoxvillecar car
    21h 8m
    $681–1,631

Fiumicino International Airport (FCO) to Mcghee Tyson Airport (TYS) flights

Calendar61Weekly Planes
Duration14h 26mAverage Duration
Ticket$611Cheapest Price
See schedules

Questions & Answers

Map of how to get from Rome to Knoxville.ExpandLaunch map view
  • Distance: 4,944 mi
  • Duration: 15h 24m

What companies run services between Rome, Italy and Knoxville, TN, USA?

Delta, United Airlines, and two other airlines fly from Fiumicino International Airport (FCO) to Mcghee Tyson Airport (TYS) every 3 hours.

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