There are 7 ways to get from Rome to Mainz by plane, train (Trenitalia), bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Frankfurt
best- Fly from Fiumicino International Airport (FCO) to Frankfurt (FRA)plane FCO - FRA
4h 51m€53–156Train
- Take the train from Roma Termini to Milano Centraletrain
- Take the train from Milano Centrale to Mannheim Hbftrain Ec
- Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain S5 / ...
12h 30m€202–347Bus
- Take the bus from Roma Prenestina A1 to Wiesbaden Gartenfeldstraße P+Rbus
18h 6m€158–214Drive 1,231.4 km
- Drive from Rome to Mainzcar 1,231.4 km
11h 29m€200–288Fly to Stuttgart Airport, train
- Fly from Fiumicino International Airport (FCO) to Stuttgart Airport (STR)plane FCO - STR
- Take the train from Hauptbahnhof to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain
7h 29m€100–275Fly to Hahn, bus
- Fly from Fiumicino International Airport (FCO) to Hahn (HHN)plane FCO - HHN
- Take the bus from Hahn to Mainz, Hauptbahnhofbus
6h 43m€68–271Bus via Frankfurt am Main
- Take the bus from Roma, Autostazione Tiburtina to Frankfurt central train stationbus N77
21h 48m€125–202
Rome to Mainz by train
Comparing Your Travel Options
The cheapest way to get from Rome to Mainz is to fly which costs €50 - €160 and takes 4h 51m.
The fastest way to get from Rome to Mainz is to fly which takes 4h 51m and costs €50 - €160.
No, there is no direct bus from Rome to Mainz. However, there are services departing from Roma Prenestina A1 and arriving at Wiesbaden-Mainz-Kastel Bahnhof via Wiesbaden Hauptbahnhof. The journey, including transfers, takes approximately 18h 6m.
No, there is no direct train from Rome to Mainz. However, there are services departing from Roma Termini and arriving at Mainz, Hauptbahnhof via Milano Centrale and Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 12h 30m.
The distance between Rome and Mainz is 1019 km. The road distance is 1231.4 km.
The best way to get from Rome to Mainz without a car is to train which takes 12h 30m and costs €200 - €350.
It takes approximately 4h 51m to get from Rome to Mainz, including transfers.
Rome to Mainz bus services, operated by Onebus, depart from Roma Prenestina A1 station.
Rome to Mainz train services, operated by ItaloTreno, depart from Roma Termini station.
The best way to get from Rome to Mainz is to fly which takes 4h 51m and costs €50 - €160. Alternatively, you can train, which costs €200 - €350 and takes 12h 30m, you could also bus, which costs €150 - €220 and takes 18h 6m.
What companies run services between Rome, Italy and Mainz, Germany?
easyJet, ITA Airways, and three other airlines fly from Fiumicino International Airport (FCO) to Frankfurt (FRA) every 2 hours. Alternatively, you can take a train from Roma Termini to Mainz, Hauptbahnhof via Milano Centrale, Mannheim Hbf, and Mannheim, Hauptbahnhof in around 12h 30m.
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Frankfurt
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- €70–130
Flights from Fiumicino International Airport to Frankfurt via Munich
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €75–130
Flights from Fiumicino International Airport to Frankfurt via Milan Linate
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- €75–400
Flights from Fiumicino International Airport to Frankfurt via Florence
- Ave. Duration
- 3h 25m
- When
- Thursday and Friday
- Estimated price
- €120–400
Flights from Fiumicino International Airport to Stuttgart Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- €70–150
Flights from Fiumicino International Airport to Stuttgart Airport via Milan Linate
- Ave. Duration
- 3h 30m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €70–240
- Website
- lufthansa.com
Flights from Fiumicino International Airport to Frankfurt
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- €70–130
Flights from Fiumicino International Airport to Frankfurt via Munich
- Ave. Duration
- 3h 37m
- When
- Every day
- Estimated price
- €70–130
Flights from Fiumicino International Airport to Frankfurt via Milan Linate
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €75–130
Flights from Fiumicino International Airport to Frankfurt via Florence
- Ave. Duration
- 3h 25m
- When
- Thursday and Friday
- Estimated price
- €120–400
Flights from Fiumicino International Airport to Stuttgart Airport via Munich
- Ave. Duration
- 3h 45m
- When
- Friday, Sunday, Monday, Tuesday, Wednesday, and Saturday
- Estimated price
- €70–320
- Website
- eurowings.com
Flights from Fiumicino International Airport to Stuttgart Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- €70–150
- Website
- ryanair.com
Flights from Fiumicino International Airport to Hahn
- Ave. Duration
- 2h
- When
- Monday, Thursday, Saturday, and Sunday
- Estimated price
- €50–250
Flights from Fiumicino International Airport to Hahn via Palermo
- Ave. Duration
- 4h 50m
- When
- Tuesday and Sunday
- Estimated price
- €70–280
- Website
- easyjet.com
Flights from Fiumicino International Airport to Frankfurt
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- €45–120
- Website
- condor.com
Flights from Fiumicino International Airport to Frankfurt
- Ave. Duration
- 1h 45m
- When
- Friday
- Estimated price
- €70–160
- Website
- swiss.com
Flights from Fiumicino International Airport to Stuttgart Airport via Zurich
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €75–310
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €70–120
- Website
- Italo Treno
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Milano Centrale to Mannheim Hbf
- Ave. Duration
- 6h 47m
- Frequency
- Once daily
- Estimated price
- €120–180
- Website
- Trenitalia Eurocity
- 1st Class
- €120–180
- 2nd Class
- €120–160
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 23m
- Frequency
- Hourly
- Estimated price
- €13–55
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 23m
- Frequency
- Hourly
- Estimated price
- €13–55
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 51m
- Frequency
- Every 3 hours
- Estimated price
- €12–27
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- Hourly
- Estimated price
- €18–40
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 51m
- Frequency
- Every 3 hours
- Estimated price
- €12–27
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 52 min
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Schedules at
- Süwex
Train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 52 min
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Schedules at
- Süwex
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Once daily
- Estimated price
- €11–23
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Roma Prenestina A1 to Wiesbaden Gartenfeldstraße P+R
- Ave. Duration
- 17h 32m
- Frequency
- Once a week
- Estimated price
- €150–210
- Website
- Onebus
- Phone
- +49 (0) 6543 5019-400
- [email protected]
- Website
- Bohr
Bus from Hahn to Mainz, Hauptbahnhof
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €14–16
- Schedules at
- Bohr
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Frankfurt central train station
- Ave. Duration
- 20h 55m
- Frequency
- Once daily
- Estimated price
- €110–180
- Website
- Flixbus
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Booking & Getting There
Rome to Mainz bus services, operated by Onebus, arrive at Wiesbaden Gartenfeldstraße P+R station.
Rome to Mainz train services, operated by ItaloTreno, arrive at Milano Centrale station.
Yes, the driving distance between Rome to Mainz is 1231 km. It takes approximately 11h 29m to drive from Rome to Mainz.
Book your Rome to Mainz train tickets online with Omio.
Book your Rome to Mainz bus tickets online with Omio.
There are 1243+ hotels available in Mainz.






























