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How to get fromRome to Mainzby plane, train (Trenitalia), bus, car, or train

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There are 7 ways to get from Rome to Mainz by plane, train (Trenitalia), bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Frankfurt

    best
    1. Fly from Fiumicino International Airport (FCO) to Frankfurt (FRA)plane plane FCO - FRA
    4h 55m
    €59–159

  2. Train via Basel

    1. Take the train from Roma Termini to Milano Centraletrain train
    2. Take the train from Milano Centrale to Basel Sbbtrain train Ec
    3. Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain train 12 / ...
    4. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train 55 / ...
    11h 50m
    €205–518

  3. Bus via Offenbach

    1. Take the bus from Roma Prenestina A1 to Mühlheim am Mainbus bus
    13h 36m

  4. Drive 1,231.4 km

    1. Drive from Rome to Mainzcar car 1,231.4 km
    11h 29m
    €194–280

  5. Fly to Stuttgart Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Stuttgart Airport (STR)plane plane FCO - STR
    2. Take the train from Hauptbahnhof to Frankfurttrain train
    7h 7m
    €97–345

  6. Train

    1. Take the train from Roma Termini to Milano Centraletrain train Fr / ...
    2. Take the train from Milano Centrale to Mannheim Hbftrain train Ec
    3. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    13h 8m
    €205–365

  7. Bus

    1. Take the bus from Roma, Autostazione Tiburtina to Frankfurt central train stationbus bus N77
    21h 48m
    €117–195

Rome to Mainz by train

Calendar14Weekly Trains
Duration13h 8mAverage Duration
Ticket€205Cheapest Price
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Questions & Answers

Map of how to get from Rome to Mainz.ExpandLaunch map view
  • Distance: 1,018.9 km
  • Duration: 4h 55m

What companies run services between Rome, Italy and Mainz, Germany?

ITA Airways, easyJet, and two other airlines fly from Fiumicino International Airport (FCO) to Frankfurt (FRA) hourly. Alternatively, you can take a train from Roma Termini to Mainz, Hauptbahnhof via Milano Centrale, Basel SBB, and Mannheim, Hauptbahnhof in around 11h 50m.

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Train operators
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Want to know more about travelling around Germany

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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