There are 6 ways to get from Rome to Melpignano by train (Trenitalia), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Trenitalia)
best- Take the train from Roma Termini to Leccetrain Fr / ...
7h 43m€90–149Bus via Maglie Piazzale Megapark
cheapest- Take the bus from Rome Tiburtina Largo Mazzoni to Maglie Piazzale Megaparkbus Itabus
10h 40m€36–61Bus
- Take the bus from Roma, Autostazione Tiburtina to Magliebus N570 / ...
10h 15m€59–86Drive 597.1 km
- Drive from Rome to Melpignanocar 597.1 km
6h 44m€97–140Fly to Brindisi Airport, line 463 bus
- Fly from Fiumicino International Airport (FCO) to Brindisi Airport (BDS)plane FCO - BDS
- Take the bus from Lecce to Melpignanobus
5h 51m€42–199Fly to Bari Karol Wojtyła Airport, train, line 463 bus
- Fly from Fiumicino International Airport (FCO) to Bari Karol Wojtyła Airport (BRI)plane FCO - BRI
- Take the train from Bari Centrale to Leccetrain
- Take the bus from Lecce to Melpignanobus
7h 37m€53–190
Rome to Melpignano by train and bus (Trenitalia)
Comparing Your Travel Options
The cheapest way to get from Rome to Melpignano is to bus via Maglie Piazzale Megapark which costs €35 - €65 and takes 10h 40m.
The fastest way to get from Rome to Melpignano is to fly and line 463 bus which takes 5h 51m and costs €40 - €200.
No, there is no direct bus from Rome to Melpignano. However, there are services departing from Roma, Autostazione Tiburtina and arriving at Melpignano via Maglie. The journey, including transfers, takes approximately 10h 15m.
No, there is no direct train from Rome to Melpignano. However, there are services departing from Roma Termini and arriving at Lecce via . The journey, including transfers, takes approximately 7h 43m.
The distance between Rome and Melpignano is 659 km. The road distance is 597.1 km.
The best way to get from Rome to Melpignano without a car is to train which takes 7h 43m and costs €90 - €150.
It takes approximately 7h 43m to get from Rome to Melpignano, including transfers.
Rome to Melpignano bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Rome to Melpignano train services, operated by Trenitalia Frecce, depart from Roma Termini station.
The best way to get from Rome to Melpignano is to train which takes 7h 43m and costs €90 - €150. Alternatively, you can bus, which costs €55 - €90 and takes 10h 15m.
What companies run services between Rome, Italy and Melpignano, Italy?
Trenitalia Frecce operates a train from Roma Termini to Lecce 5 times a day. Tickets cost €85–150 and the journey takes 5h 50m. Alternatively, FlixBus operates a bus from Roma, Autostazione Tiburtina to Maglie twice daily. Tickets cost €55–90 and the journey takes 8h 50m.
- Website
- ryanair.com
Flights from Fiumicino International Airport to Brindisi Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €28–160
Flights from Fiumicino International Airport to Bari Karol Wojtyła Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €24–120
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Brindisi Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €55–180
Flights from Fiumicino International Airport to Bari Karol Wojtyła Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €55–160
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Roma Termini to Lecce
- Ave. Duration
- 5h 50m
- Frequency
- 5 times a day
- Estimated price
- €85–150
- Website
- Trenitalia Frecce
Train from Bari Centrale to Lecce
- Ave. Duration
- 1h 24m
- Frequency
- Hourly
- Estimated price
- €20–35
- Website
- Trenitalia Frecce
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Bari Centrale to Lecce
- Ave. Duration
- 1h 53m
- Frequency
- Hourly
- Estimated price
- €17–25
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Bari Centrale to Lecce
- Ave. Duration
- 1h 42m
- Frequency
- 5 times a day
- Estimated price
- €16–29
- Website
- Trenitalia Intercity
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Maglie
- Ave. Duration
- 8h 50m
- Frequency
- Twice daily
- Estimated price
- €55–90
- Website
- Flixbus
- Phone
- 800 07 9090
- Website
- fssudest.it
Bus from Lecce to Melpignano
- Ave. Duration
- 53 min
- Frequency
- Once daily
- Estimated price
- €3–4
- Schedules at
- fssudest.it
Bus from Lecce to Melpignano
- Ave. Duration
- 53 min
- Frequency
- Once daily
- Estimated price
- €3–4
- Schedules at
- fssudest.it
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Rome Tiburtina Largo Mazzoni to Maglie Piazzale Megapark
- Ave. Duration
- 9h 15m
- Frequency
- 4 times a day
- Estimated price
- €30–60
- Website
- Itabus S.p.A.
Want to know more about travelling around Italy
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Booking & Getting There
Rome to Melpignano bus services, operated by FlixBus, arrive at Maglie station.
Rome to Melpignano train services, operated by Trenitalia Frecce, arrive at Lecce station.
Yes, the driving distance between Rome to Melpignano is 597 km. It takes approximately 6h 44m to drive from Rome to Melpignano.
Book your Rome to Melpignano train tickets online with Omio.
There are 4388+ hotels available in Melpignano.


















