There are 6 ways to get from Rome to Melpignano by train (Trenitalia), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Trenitalia)
best- Take the train from Roma Termini to Leccetrain Fr / ...
7h 40m€97–186Fly to Brindisi Airport, train, line 463 bus
cheapest- Fly from Fiumicino International Airport (FCO) to Brindisi Airport (BDS)plane FCO - BDS
- Take the train from Brindisi to Leccetrain
- Take the bus from Lecce to Melpignanobus
6h 44m€42–194Bus
- Take the bus from Roma, Autostazione Tiburtina to Magliebus N570 / ...
10h 15m€55–90Drive 597.1 km
- Drive from Rome to Melpignanocar 597.1 km
6h 44m€94–135Bus via Maglie Piazzale Megapark
- Take the bus from Rome Tiburtina Largo Mazzoni to Maglie Piazzale Megaparkbus Itabus
10h 40m€42–77Fly to Lamezia Terme International Airport, drive
- Fly from Fiumicino International Airport (FCO) to Lamezia Terme International Airport (SUF)plane FCO - SUF
- Drive from Lamezia-Terme-Airport-SUF to Melpignanocar
7h 46m€104–241
Rome to Melpignano by train and bus (Trenitalia)
Questions & Answers
The cheapest way to get from Rome to Melpignano is to bus via Maglie Piazzale Megapark which costs €40 - €80 and takes 10h 40m.
The fastest way to get from Rome to Melpignano is to drive which takes 6h 44m and costs €90 - €140.
No, there is no direct bus from Rome to Melpignano. However, there are services departing from Roma, Autostazione Tiburtina and arriving at Melpignano via Maglie. The journey, including transfers, takes approximately 10h 15m.
No, there is no direct train from Rome to Melpignano. However, there are services departing from Roma Termini and arriving at Lecce via . The journey, including transfers, takes approximately 7h 40m.
The distance between Rome and Melpignano is 659 km. The road distance is 597.1 km.
The best way to get from Rome to Melpignano without a car is to train which takes 7h 40m and costs €95 - €190.
It takes approximately 7h 40m to get from Rome to Melpignano, including transfers.
Rome to Melpignano bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Rome to Melpignano train services, operated by Trenitalia Frecce, depart from Roma Termini station.
The best way to get from Rome to Melpignano is to train which takes 7h 40m and costs €95 - €190. Alternatively, you can bus, which costs €55 - €90 and takes 10h 15m.
What companies run services between Rome, Italy and Melpignano, Italy?
Trenitalia Frecce operates a train from Roma Termini to Lecce every 2 hours. Tickets cost €90–190 and the journey takes 5h 47m. Alternatively, FlixBus operates a bus from Roma, Autostazione Tiburtina to Maglie twice daily. Tickets cost €50–90 and the journey takes 8h 50m.
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Brindisi Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- €50–180
Flights from Fiumicino International Airport to Lamezia Terme International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- €45–160
- Website
- ryanair.com
Flights from Fiumicino International Airport to Brindisi Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €26–160
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Lecce
- Ave. Duration
- 5h 47m
- Frequency
- Every 2 hours
- Estimated price
- €90–190
- Schedules at
- trenitalia.com
Train from Brindisi to Lecce
- Ave. Duration
- 23 min
- Frequency
- Hourly
- Estimated price
- €5–12
- Schedules at
- trenitalia.com
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Brindisi to Lecce
- Ave. Duration
- 30 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–8
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Brindisi to Lecce
- Ave. Duration
- 24 min
- Frequency
- Every 2 hours
- Estimated price
- €4–9
- Website
- https://www.trenitalia.com/en.html
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Roma, Autostazione Tiburtina to Maglie
- Ave. Duration
- 8h 50m
- Frequency
- Twice daily
- Estimated price
- €50–90
- Website
- https://www.flixbus.co.uk
- Phone
- 800 07 9090
- Website
- fseonline.it
Bus from Lecce to Melpignano
- Ave. Duration
- 53 min
- Frequency
- 3 times a day
- Estimated price
- €3–5
- Schedules at
- fseonline.it
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Rome Tiburtina Largo Mazzoni to Maglie Piazzale Megapark
- Ave. Duration
- 9h 15m
- Frequency
- 4 times a day
- Estimated price
- €40–80
- Website
- https://www.itabus.it/en/home
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Want to know more about Flixbus?
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More Questions & Answers
Rome to Melpignano bus services, operated by FlixBus, arrive at Maglie station.
Rome to Melpignano train services, operated by Trenitalia Frecce, arrive at Lecce station.
Yes, the driving distance between Rome to Melpignano is 597 km. It takes approximately 6h 44m to drive from Rome to Melpignano.
There are 5953+ hotels available in Melpignano.


















