There are 6 ways to get from Rome to San Sano by train (Trenitalia), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Montevarchi-Terran. (Trenitalia)
best- Take the train from Roma Termini to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Montevarchi-Terran.train Re / ...
3h 14m€89–141Bus
cheapest- Take the bus from Rome Tiburtina Largo Mazzoni to Siena Central Train Stationbus Itabus
4h 30m€14–31Drive 238.5 km
- Drive from Rome to San Sanocar 238.5 km
2h 28m€38–55Train (Trenitalia)
- Take the train from Roma Termini to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
5h 12m€41–81Train via Chiusi (Trenitalia)
- Take the train from Roma Termini to Chiusi-Chianciano T.train Re / ...
- Take the train from Chiusi-Chianciano T. to Sienatrain Re / ...
5h 22m€28–47Bus via Anagnina
- Take the bus from Roma - Via Vincenzo Giudice to Sienabus
7h 8m€24–28
Rome to San Sano by bus
Comparing Your Travel Options
The cheapest way to get from Rome to San Sano is to bus which costs €14 - €35 and takes 4h 30m.
The fastest way to get from Rome to San Sano is to drive which takes 2h 28m and costs €35 - €55.
No, there is no direct bus from Rome to San Sano. However, there are services departing from Rome Tiburtina Largo Mazzoni and arriving at S.Sano via Siena Autostazione. The journey, including transfers, takes approximately 4h 30m.
No, there is no direct train from Rome to San Sano. However, there are services departing from Roma Termini and arriving at Montevarchi-Terran. via Firenze S.M.N.. The journey, including transfers, takes approximately 3h 14m.
The distance between Rome and San Sano is 340 km. The road distance is 238.5 km.
The best way to get from Rome to San Sano without a car is to train via Montevarchi-Terran. which takes 3h 14m and costs €85 - €150.
It takes approximately 3h 14m to get from Rome to San Sano, including transfers.
Rome to San Sano bus services, operated by Itabus S.p.A., depart from Rome Tiburtina Largo Mazzoni station.
Rome to San Sano train services, operated by Trenitalia Frecce, depart from Roma Termini station.
The best way to get from Rome to San Sano is to train via Montevarchi-Terran. which takes 3h 14m and costs €85 - €150. Alternatively, you can bus, which costs €14 - €35 and takes 4h 30m.
What companies run services between Rome, Italy and San Sano, Italy?
You can take a train from Roma Termini to San Sano via Firenze S.M.N. and Montevarchi-Terran. in around 3h 14m. Alternatively, Itabus S.p.A. operates a bus from Rome Tiburtina Largo Mazzoni to Siena Central Train Station 5 times a week. Tickets cost €12–21 and the journey takes 2h 50m. FlixBus also services this route twice daily.
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 37m
- Frequency
- Every 20 minutes
- Estimated price
- €35–65
- Website
- Trenitalia Frecce
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 37m
- Frequency
- Every 20 minutes
- Estimated price
- €35–65
- Website
- Trenitalia Frecce
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Rome Tiburtina Largo Mazzoni to Siena Central Train Station
- Ave. Duration
- 2h 50m
- Frequency
- 5 times a week
- Estimated price
- €12–21
- Website
- Itabus S.p.A.
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
Booking & Getting There
Rome to San Sano bus services, operated by Itabus S.p.A., arrive at Siena Central Train Station.
Rome to San Sano train services, operated by Trenitalia Frecce, arrive at Firenze S.M.N. station.
Yes, the driving distance between Rome to San Sano is 238 km. It takes approximately 2h 28m to drive from Rome to San Sano.
There are 2493+ hotels available in San Sano.






