There are 6 ways to get from Rome to Santo Spirito by train (Trenitalia), bus, car, plane, rideshare, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Roma Termini to Firenze S.M.N.train Fr
1h 52m€28–80Rideshare
cheapest- Take the rideshare from Rome to Florence270.4 km
3h 22m€10–25Bus
- Take the bus from Roma, Autostazione Tiburtina to Florencebus N531 / ...
3h 46m€20–35Drive 269.4 km
- Drive from Rome to Santo Spiritocar 269.4 km
2h 40m€43–62Fly to Florence Peretola Airport
- Fly from Fiumicino International Airport (FCO) to Florence Peretola Airport (FLR)plane FCO - FLR
3h 6m€66–208Fly to Bologna Guglielmo Marconi Airport, train
- Fly from Fiumicino International Airport (FCO) to Bologna Guglielmo Marconi Airport (BLQ)plane FCO - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
3h 51m€59–213
Rome to Santo Spirito by train and foot
Questions & Answers
The cheapest way to get from Rome to Santo Spirito is to rideshare which costs €10 - €25 and takes 3h 22m.
The fastest way to get from Rome to Santo Spirito is to train which takes 1h 52m and costs €28 - €80.
Yes, there is a direct bus departing from Roma, Autostazione Tiburtina and arriving at Florence. Services depart four times a day, and operate every day. The journey takes approximately 3h 25m.
Yes, there is a direct train departing from Roma Termini and arriving at Firenze S.M.N.. Services depart every 30 minutes, and operate every day. The journey takes approximately 1h 37m.
The distance between Rome and Santo Spirito is 262 km. The road distance is 269.4 km.
The best way to get from Rome to Santo Spirito without a car is to train which takes 1h 52m and costs €28 - €80.
The train from Rome Termini to Firenze S.M.N. takes 1h 37m including transfers and departs every 30 minutes.
Rome to Santo Spirito bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Rome to Santo Spirito train services, operated by Trenitalia Frecce, depart from Roma Termini station.
The best way to get from Rome to Santo Spirito is to train which takes 1h 52m and costs €28 - €80. Alternatively, you can bus, which costs €20 - €35 and takes 3h 46m, you could also fly, which costs €65 - €210 and takes 3h 6m.
What companies run services between Rome, Italy and Santo Spirito, Tuscany, Italy?
Trenitalia Frecce operates a train from Roma Termini to Firenze S.M.N. every 30 minutes. Tickets cost €35–80 and the journey takes 1h 37m. Three other operators also service this route. Alternatively, FlixBus operates a bus from Roma, Autostazione Tiburtina to Florence 4 times a day. Tickets cost €20–35 and the journey takes 3h 25m.
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Florence Peretola Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- €60–180
Flights from Fiumicino International Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 2m
- When
- Every day
- Estimated price
- €55–150
- Phone
- +39 06 68475475
- Website
- Trenitalia Frecce
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 37m
- Frequency
- Every 30 minutes
- Estimated price
- €35–80
- Schedules at
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €13–27
- Schedules at
- Trenitalia Frecce
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Florence
- Ave. Duration
- 3h 25m
- Frequency
- 4 times a day
- Estimated price
- €20–35
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar
Rideshare from Rome to Florence
- Ave. Duration
- 3h 12m
- Frequency
- Hourly
- Estimated price
- €10–25
- Schedules at
- BlaBlaCar
Want to know more about travelling around Italy
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More Questions & Answers
Rome to Santo Spirito bus services, operated by FlixBus, arrive at Florence station.
Rome to Santo Spirito train services, operated by Trenitalia Frecce, arrive at Firenze S.M.N. station.
Yes, the driving distance between Rome to Santo Spirito is 269 km. It takes approximately 2h 40m to drive from Rome to Santo Spirito.
Book your Rome to Santo Spirito train tickets online with Omio.
There are 8347+ hotels available in Santo Spirito.
Check out Blablacar's carpooling service for rideshare options between Rome and Santo Spirito. A great option if you don't have a driver's licence or want to avoid public transport.