Rome2Rio

How to get fromRome to Speyerby plane, train, train (Trenitalia), bus, or car

Find Transport to Speyer

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There are 6 ways to get from Rome to Speyer by plane, train, train (Trenitalia), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Frankfurt, train

    best
    1. Fly from Fiumicino International Airport (FCO) to Frankfurt (FRA)plane plane FCO - FRA
    2. Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain train
    6h 2m
    €60–181
  2. Train

    1. Take the train from Roma Termini to Milano Centraletrain train
    2. Take the train from Milano Centrale to Karlsruhe Hbftrain train Ec
    3. Take the train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOBtrain train S3 / ...
    12h 19m
    €197–357
  3. Bus

    1. Take the bus from Roma Prenestina A1 to Karlsruhe Central Bus Stationbus bus
    15h 16m
    €136–204
  4. Drive  1,143.2 km

    1. Drive from Rome to Speyercar car 1,143.2 km
    10h 51m
    €186–268
  5. Fly to Stuttgart Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Stuttgart Airport (STR)plane plane FCO - STR
    2. Take the train from Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    6h 38m
    €92–243
  6. Bus, train

    1. Take the bus from Roma, Autostazione Tiburtina to Karlsruhe central train stationbus bus N77
    2. Take the train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOBtrain train S3 / ...
    20h 32m
    €122–229

Rome to Speyer by bus and train

Calendar10Weekly Services
Duration20h 32mAverage Duration
Ticket€122Cheapest Price
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Comparing Your Travel Options

What companies run services between Rome, Italy and Speyer, Germany?

You can take a train from Roma Termini to Speyer, Hbf/ZOB via Milano Centrale, Karlsruhe Hbf, and Karlsruhe Hauptbahnhof in around 12h 19m. Alternatively, Onebus operates a bus from Roma Prenestina A1 to Karlsruhe Central Bus Station once a week. Tickets cost €130–180 and the journey takes 13h 45m.

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