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How to get fromRome to Speyerby plane, train, train (Trenitalia), bus, or car

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There are 9 ways to get from Rome to Speyer by plane, train, train (Trenitalia), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Frankfurt, train

    best
    1. Fly from Fiumicino International Airport (FCO) to Frankfurt (FRA)plane plane FCO - FRA
    2. Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain train
    6h 6m
    €67–203
  2. Train

    1. Take the train from Roma Termini to Milano Centraletrain train Fr / ...
    2. Take the train from Milano Centrale to Karlsruhe Hbftrain train Ec
    3. Take the train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOBtrain train Re4
    11h 44m
    €194–353
  3. Bus

    1. Take the bus from Roma Prenestina A1 to Karlsruhe Central Bus Stationbus bus
    15h 20m
  4. Drive 1,143.2 km

    1. Drive from Rome to Speyercar car 1,143.2 km
    10h 51m
    €180–260
  5. Fly to Stuttgart Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Stuttgart Airport (STR)plane plane FCO - STR
    2. Take the train from Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    6h 31m
    €90–291
  6. Fly to Cologne Bonn Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Cologne Bonn Airport (CGN)plane plane FCO - CGN
    2. Take the train from Köln Messe/Deutz Bf to Mannheim, Hauptbahnhoftrain train
    7h 35m
    €117–394
  7. Fly to Munich International Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Munich International Airport (MUC)plane plane FCO - MUC
    2. Take the train from München Hbf to Mannheim, Hauptbahnhoftrain train
    8h 46m
    €102–453
  8. Train via Basel

    1. Take the train from Roma Termini to Milano Centraletrain train
    2. Take the train from Milano Centrale to Basel Sbbtrain train Ec
    3. Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain train 12 / ...
    11h 45m
    €199–486
  9. Bus, train

    1. Take the bus from Roma, Autostazione Tiburtina to Karlsruhe central train stationbus bus N77
    2. Take the train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOBtrain train Re4
    19h 50m
    €115–189

Rome to Speyer by train

Calendar14Weekly Trains
Duration11h 44mAverage Duration
Ticket€194Cheapest Price
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Questions & Answers

What companies run services between Rome, Italy and Speyer, Germany?

You can take a train from Roma Termini to Speyer, Hbf/ZOB via Milano Centrale, Karlsruhe Hbf, and Karlsruhe Hauptbahnhof in around 11h 44m. Alternatively, Onebus operates a bus from Roma Prenestina A1 to Karlsruhe Central Bus Station once a week, and the journey takes 13h 48m.

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