There are 9 ways to get from Rome to Speyer by plane, train, train (Trenitalia), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Frankfurt, train
best- Fly from Fiumicino International Airport (FCO) to Frankfurt (FRA)plane FCO - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
6h 6m€57–173Train via Basel
- Take the train from Roma Termini to Milano Centraletrain
- Take the train from Milano Centrale to Basel Sbbtrain Ec
- Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain 12 / ...
11h 45m€191–364Bus
- Take the bus from Roma Prenestina A1 to Karlsruhe Central Bus Stationbus
15h 45m€132–180Drive 1,143.2 km
- Drive from Rome to Speyercar 1,143.2 km
10h 51m€183–264Fly to Stuttgart Airport, train
- Fly from Fiumicino International Airport (FCO) to Stuttgart Airport (STR)plane FCO - STR
- Take the train from Hauptbahnhof to Mannheim, Hauptbahnhoftrain
6h 28m€82–209Fly to Cologne Bonn Airport, train
- Fly from Fiumicino International Airport (FCO) to Cologne Bonn Airport (CGN)plane FCO - CGN
- Take the train from Köln Messe/Deutz Bf to Mannheim, Hauptbahnhoftrain
7h 39m€116–313Fly to Munich International Airport, train
- Fly from Fiumicino International Airport (FCO) to Munich International Airport (MUC)plane FCO - MUC
- Take the train from München Hbf to Mannheim, Hauptbahnhoftrain
8h 46m€102–291Train
- Take the train from Roma Termini to Milano Centraletrain Fr / ...
- Take the train from Milano Centrale to Karlsruhe Hbftrain Ec
- Take the train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOBtrain S3 / ...
12h 37m€184–328Bus, train
- Take the bus from Roma, Autostazione Tiburtina to Karlsruhe central train stationbus N77
- Take the train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOBtrain S3 / ...
20h 37m€104–169
Rome to Speyer by train
Comparing Your Travel Options
The cheapest way to get from Rome to Speyer is to fly and train which costs €55 - €180 and takes 6h 6m.
The fastest way to get from Rome to Speyer is to fly and train which takes 6h 6m and costs €55 - €180.
No, there is no direct bus from Rome to Speyer. However, there are services departing from Roma Prenestina A1 and arriving at Speyer, Domplatz via Neulußheim, Bahnhof. The journey, including transfers, takes approximately 15h 45m.
No, there is no direct train from Rome to Speyer. However, there are services departing from Roma Termini and arriving at Speyer, Hbf/ZOB via Milano Centrale, Basel SBB and Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 11h 45m.
The distance between Rome and Speyer is 1087 km. The road distance is 1143.2 km.
The best way to get from Rome to Speyer without a car is to train via Basel which takes 11h 45m and costs €190 - €370.
It takes approximately 6h 6m to get from Rome to Speyer, including transfers.
Rome to Speyer bus services, operated by Onebus, depart from Roma Prenestina A1 station.
Rome to Speyer train services, operated by ItaloTreno, depart from Roma Termini station.
The best way to get from Rome to Speyer is to train via Basel which takes 11h 45m and costs €190 - €370. Alternatively, you can bus, which costs €130 - €180 and takes 15h 45m.
What companies run services between Rome, Italy and Speyer, Germany?
You can take a train from Roma Termini to Speyer, Hbf/ZOB via Milano Centrale, Basel SBB, and Mannheim, Hauptbahnhof in around 11h 45m. Alternatively, Onebus operates a bus from Roma Prenestina A1 to Karlsruhe Central Bus Station once a week. Tickets cost €130–180 and the journey takes 13h 48m.
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Frankfurt
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- €75–120
Flights from Fiumicino International Airport to Stuttgart Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €70–150
Flights from Fiumicino International Airport to Stuttgart Airport via Milan Linate
- Ave. Duration
- 3h 45m
- When
- Sunday
- Estimated price
- €65–220
Flights from Fiumicino International Airport to Stuttgart Airport via Zurich
- Ave. Duration
- 3h 50m
- When
- Tuesday to Sunday
- Estimated price
- €85–300
Flights from Fiumicino International Airport to Cologne Bonn Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- €90–200
Flights from Fiumicino International Airport to Munich International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €40–260
Flights from Fiumicino International Airport to Munich International Airport via Milan Linate
- Ave. Duration
- 3h 38m
- When
- Every day
- Estimated price
- €75–110
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €13–26
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 6m
- Frequency
- Hourly
- Estimated price
- €45–95
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €19–40
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Köln Messe/Deutz Bf to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 23m
- Frequency
- Hourly
- Estimated price
- €40–90
- Website
- Deutsche Bahn Intercity (DB IC)
Train from München Hbf to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 45m
- Frequency
- Hourly
- Estimated price
- €60–130
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Roma Prenestina A1 to Karlsruhe Central Bus Station
- Ave. Duration
- 13h 48m
- Frequency
- Once a week
- Estimated price
- €130–180
- Website
- Onebus
Want to know more about travelling around Germany
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Rome to Speyer bus services, operated by Onebus, arrive at Karlsruhe Central Bus Station.
Rome to Speyer train services, operated by ItaloTreno, arrive at Milano Centrale station.
Yes, the driving distance between Rome to Speyer is 1143 km. It takes approximately 10h 51m to drive from Rome to Speyer.
Book your Rome to Speyer train tickets online with Omio.
There are 1486+ hotels available in Speyer.





