There are 6 ways to get from Rome to Speyer by plane, train, train (Trenitalia), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Frankfurt, train
best- Fly from Fiumicino International Airport (FCO) to Frankfurt (FRA)plane FCO - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
6h 2m€60–181Train
- Take the train from Roma Termini to Milano Centraletrain
- Take the train from Milano Centrale to Karlsruhe Hbftrain Ec
- Take the train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOBtrain S3 / ...
12h 19m€197–357Bus
- Take the bus from Roma Prenestina A1 to Karlsruhe Central Bus Stationbus
15h 16m€136–204Drive 1,143.2 km
- Drive from Rome to Speyercar 1,143.2 km
10h 51m€186–268Fly to Stuttgart Airport, train
- Fly from Fiumicino International Airport (FCO) to Stuttgart Airport (STR)plane FCO - STR
- Take the train from Hauptbahnhof to Mannheim, Hauptbahnhoftrain
6h 38m€92–243Bus, train
- Take the bus from Roma, Autostazione Tiburtina to Karlsruhe central train stationbus N77
- Take the train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOBtrain S3 / ...
20h 32m€122–229
Rome to Speyer by bus and train
Comparing Your Travel Options
The cheapest way to get from Rome to Speyer is to fly and train which costs €60 - €190 and takes 6h 2m.
The fastest way to get from Rome to Speyer is to fly and train which takes 6h 2m and costs €60 - €190.
No, there is no direct bus from Rome to Speyer. However, there are services departing from Roma Prenestina A1 and arriving at Speyer, Domplatz via Neulußheim, Bahnhof. The journey, including transfers, takes approximately 15h 16m.
No, there is no direct train from Rome to Speyer. However, there are services departing from Roma Termini and arriving at Speyer, Hbf/ZOB via Milano Centrale and Karlsruhe Hauptbahnhof. The journey, including transfers, takes approximately 12h 19m.
The distance between Rome and Speyer is 1087 km. The road distance is 1143.2 km.
The best way to get from Rome to Speyer without a car is to train which takes 12h 19m and costs €190 - €360.
It takes approximately 6h 2m to get from Rome to Speyer, including transfers.
Rome to Speyer bus services, operated by Onebus, depart from Roma Prenestina A1 station.
Rome to Speyer train services, operated by ItaloTreno, depart from Roma Termini station.
The best way to get from Rome to Speyer is to train which takes 12h 19m and costs €190 - €360. Alternatively, you can bus, which costs €130 - €210 and takes 15h 16m.
What companies run services between Rome, Italy and Speyer, Germany?
You can take a train from Roma Termini to Speyer, Hbf/ZOB via Milano Centrale, Karlsruhe Hbf, and Karlsruhe Hauptbahnhof in around 12h 19m. Alternatively, Onebus operates a bus from Roma Prenestina A1 to Karlsruhe Central Bus Station once a week. Tickets cost €130–180 and the journey takes 13h 45m.
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Frankfurt
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- €70–130
Flights from Fiumicino International Airport to Frankfurt via Munich
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €75–130
Flights from Fiumicino International Airport to Frankfurt via Milan Linate
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- €75–400
Flights from Fiumicino International Airport to Frankfurt via Florence
- Ave. Duration
- 3h 25m
- When
- Thursday and Friday
- Estimated price
- €120–400
Flights from Fiumicino International Airport to Stuttgart Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- €70–150
Flights from Fiumicino International Airport to Stuttgart Airport via Milan Linate
- Ave. Duration
- 3h 30m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €70–240
- Website
- lufthansa.com
Flights from Fiumicino International Airport to Frankfurt
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- €70–130
Flights from Fiumicino International Airport to Frankfurt via Munich
- Ave. Duration
- 3h 37m
- When
- Every day
- Estimated price
- €70–130
Flights from Fiumicino International Airport to Frankfurt via Milan Linate
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €75–130
Flights from Fiumicino International Airport to Frankfurt via Florence
- Ave. Duration
- 3h 25m
- When
- Thursday and Friday
- Estimated price
- €120–400
Flights from Fiumicino International Airport to Stuttgart Airport via Munich
- Ave. Duration
- 3h 45m
- When
- Friday, Sunday, Monday, Tuesday, Wednesday, and Saturday
- Estimated price
- €70–320
- Website
- eurowings.com
Flights from Fiumicino International Airport to Stuttgart Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- €70–150
- Website
- easyjet.com
Flights from Fiumicino International Airport to Frankfurt
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- €45–120
- Website
- condor.com
Flights from Fiumicino International Airport to Frankfurt
- Ave. Duration
- 1h 45m
- When
- Friday
- Estimated price
- €70–160
- Website
- swiss.com
Flights from Fiumicino International Airport to Stuttgart Airport via Zurich
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €75–310
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €12–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- Hourly
- Estimated price
- €18–45
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 32 min
- Frequency
- 3 times a day
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Once daily
- Estimated price
- €11–23
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €65–120
- Website
- Italo Treno
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Milano Centrale to Karlsruhe Hbf
- Ave. Duration
- 6h 17m
- Frequency
- Once daily
- Estimated price
- €110–170
- Website
- Trenitalia Eurocity
- 1st Class
- €110–170
- 2nd Class
- €110–150
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOB
- Ave. Duration
- 1h 36m
- Frequency
- Hourly
- Estimated price
- €17–75
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOB
- Ave. Duration
- 1h 36m
- Frequency
- Hourly
- Estimated price
- €17–75
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOB
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- €17–25
- Schedules at
- Süwex
Train from Karlsruhe Hauptbahnhof to Speyer, Hbf/ZOB
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- €17–25
- Schedules at
- Süwex
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Roma Prenestina A1 to Karlsruhe Central Bus Station
- Ave. Duration
- 13h 45m
- Frequency
- Once a week
- Estimated price
- €130–180
- Website
- Onebus
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Karlsruhe central train station
- Ave. Duration
- 18h 35m
- Frequency
- Once daily
- Estimated price
- €100–160
- Website
- Flixbus
Want to know more about travelling around Germany
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Rome to Speyer bus services, operated by Onebus, arrive at Karlsruhe Central Bus Station.
Rome to Speyer train services, operated by ItaloTreno, arrive at Milano Centrale station.
Yes, the driving distance between Rome to Speyer is 1143 km. It takes approximately 10h 51m to drive from Rome to Speyer.
Book your Rome to Speyer train tickets online with Omio.
There are 1467+ hotels available in Speyer.






























