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How to get fromSaco to Niagara Fallsby train, plane, bus, bus (Amtrak, Greyhound), train (Amtrak), car, or bus (Flixbus)

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There are 10 ways to get from Saco to Niagara Falls by train, plane, bus, bus (Amtrak, Greyhound), train (Amtrak), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Boston Logan Airport, fly to Buffalo Niagara International Airport, bus

    best
    1. Take the train from Saco Amtrak Station to Woburn Amtrak Stationtrain train
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    3. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    7h 6m
    $127–624

  2. Drive 507.4 mi

    cheapest
    1. Drive from Saco to Niagara Fallscar car 507.4 mi
    10h 23m
    $93–134

  3. Bus

    1. Take the bus from Portland, ME to Boston, MA - South Stationbus bus Portland / ...
    2. Take the bus from Boston to Buffalobus bus Greyhound US0171
    16h 20m
    $97–193

  4. Train

    1. Take the train from Saco Amtrak Station to Bostontrain train
    2. Take the train from Boston to Buffalo Depew Stationtrain train
    3. Take the train from Buffalo Depew Station to Niagara Falls Amtrak Stationtrain train
    16h 54m
    $205–538

  5. Fly Portland to Buffalo Niagara International Airport, bus

    1. Fly from Portland (PWM) to Buffalo Niagara International Airport (BUF)plane plane PWM - BUF
    2. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    8h 22m
    $133–726

  6. Train to Boston Logan Airport, fly to Rochester, train

    1. Take the train from Saco Amtrak Station to Woburn Amtrak Stationtrain train
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    3. Take the train from Rochester to Niagara Falls Amtrak Stationtrain train
    8h 33m
    $161–758

  7. Train to Boston Logan Airport, fly to Toronto Island Airport, bus

    1. Take the train from Saco Amtrak Station to Woburn Amtrak Stationtrain train
    2. Fly from Boston Logan Airport (BOS) to Toronto Island Airport (YTZ)plane plane BOS - YTZ
    3. Take the bus from Toronto Union Station to Niagara Falls, ONbus bus
    9h 24m
    $155–621

  8. Train to Boston Logan Airport, fly to Toronto Pearson International Airport, bus

    1. Take the train from Saco Amtrak Station to Woburn Amtrak Stationtrain train
    2. Fly from Boston Logan Airport (BOS) to Toronto Pearson International Airport (YYZ)plane plane BOS - YYZ
    3. Take the bus from Toronto Union Station to Niagara Falls, ONbus bus
    9h 45m
    $171–680

  9. Fly Portland to Toronto Island Airport, bus

    1. Fly from Portland (PWM) to Toronto Island Airport (YTZ)plane plane PWM - YTZ
    2. Take the bus from Toronto Union Station to Niagara Falls, ONbus bus
    10h 46m
    $866–1,273

  10. Bus via Ithaca

    1. Take the bus from Dyer Library to St John Stbus bus 60
    2. Take the bus from City of Portland to Springfield Union Stationbus bus
    3. Take the bus from Springfield Union Station to Ithacabus bus
    4. Take the bus from Ithaca to Niagara Falls USAbus bus
    18h 24m
    $105–177

Saco to Niagara Falls by bus

Calendar7Weekly Buses
Duration16h 20mAverage Duration
Ticket$97Cheapest Price
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Questions & Answers

Map of how to get from Saco to Niagara Falls.ExpandLaunch map view
  • Distance: 527.6 mi
  • Duration: 7h 6m

What companies run services between Saco, ME, USA and Niagara Falls, NY, USA?

You can take a bus from Dyer Library to Main Street & Pine Avenue via Portland Public Library, Portland, ME, Boston, MA - South Station, Boston, Buffalo, and Ellicott Street & MTC Static in around 16h 20m. Alternatively, you can take a train from Saco Amtrak Station to Niagara Falls Amtrak Station via Boston, North Station, Back Bay, Boston, and Buffalo Depew Station in around 16h 54m.

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