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How to get fromSacramento to Mayo Clinicby plane, bus (Greyhound), train, bus, car, or subway

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There are 9 ways to get from Sacramento to Mayo Clinic by plane, bus (Greyhound), train, bus, car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Sacramento International Airport to Rochester

    best
    1. Fly from Sacramento International Airport (SMF) to Rochester (RST)plane plane SMF - RST
    9h 9m
    $133–643

  2. Bus

    1. Take the bus from Sacramento Bus Station to Sparks Transit Centerbus bus
    2. Take the bus from Sparks Transit Center to Denver Union Stationbus bus
    3. Take the bus from Denver Union Station to Des Moinesbus bus
    4. Take the bus from Des Moines to MSP Airportbus bus
    5. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    47h 20m
    $391–689

  3. Train, bus via Portland

    1. Take the train from Sacramento to Portlandtrain train
    2. Take the train from Portland to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochester, MNbus bus
    2d 9h
    $786–1,762

  4. Drive 1,846.7 mi

    1. Drive from Sacramento to Mayo Cliniccar car 1,846.7 mi
    29h 55m
    $337–487

  5. Fly Sacramento International Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Sacramento International Airport (SMF) to Minneapolis–Saint Paul International Airport (MSP)plane plane SMF - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 31m
    $214–755

  6. Train, BART to San Francisco International Airport, fly to Rochester

    1. Take the train from Sacramento to Richmondtrain train
    2. Take the subway from Richmond to San Francisco International Airportsubway subway
    3. Fly from San Francisco International Airport (SFO) to Rochester (RST)plane plane SFO - RST
    11h 22m
    $148–587

  7. Train, BART to San Francisco International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from Sacramento to Richmondtrain train
    2. Take the subway from Richmond to San Francisco International Airportsubway subway
    3. Fly from San Francisco International Airport (SFO) to Minneapolis–Saint Paul International Airport (MSP)plane plane SFO - MSP
    4. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    10h 11m
    $209–439

  8. Train to Norman Y. Mineta San José International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from Sacramento to Santa Clara Amtraktrain train
    2. Fly from Norman Y. Mineta San José International Airport (SJC) to Minneapolis–Saint Paul International Airport (MSP)plane plane SJC - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    10h 45m
    $538–792

  9. Train, bus

    1. Take the train from Sacramento to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    2d 12h
    $828–1,659

Sacramento to Mayo Clinic by train, bus, and foot

Calendar7Weekly Services
Duration2d 9hAverage Duration
Ticket$786Cheapest Price
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Questions & Answers

Map of how to get from Sacramento to Mayo Clinic.ExpandLaunch map view
  • Distance: 1,564.5 mi
  • Duration: 9h 9m

What companies run services between Sacramento, CA, USA and Mayo Clinic, MN, USA?

Delta, American Airlines, and United Airlines fly from Sacramento International Airport (SMF) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Sacramento Bus Station to Mayo Clinic via Sparks Transit Center, Denver Union Station, Des Moines, MSP Airport, Minneapolis / St Paul Airport, and Groome Transportation Office - Rochester in around 47h 20m.

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