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How to get fromSaint Augustine to Key West, FLby car, plane, taxi, train, bus, shuttle, or bus (Flixbus, Greyhound)

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There are 7 ways to get from Saint Augustine to Key West, FL by car, plane, taxi, train, bus, shuttle, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Orlando Sanford, fly to Key West International Airport

    best
    1. Drive from Saint Augustine to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    4h 16m
    $131–393

  2. Drive  468.1 mi

    cheapest
    1. Drive from Saint Augustine to Key West, FLcar car 468.1 mi
    8h 39m
    $86–124

  3. Taxi, train, bus, shuttle

    1. Take the taxi from Saint Augustine to Jacksonvilletaxi taxi
    2. Take the train from Jacksonville to Hollywood Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take a shuttle bus from Big Pine Key, FL to Key West, FLshuttle bus
    16h 45m
    $452–629

  4. Bus, shuttle

    1. Take the bus from St. Johns Adminsistration to JRTC - Express Selectbus bus
    2. Take the bus from Jacksonville to Miami Golden Gladesbus bus
    3. Take a shuttle bus from Bayside Marketplace to Plaza Hotelshuttle bus
    17h 24m
    $135–175

  5. Bus to Jacksonville, fly to Key West International Airport

    1. Take the bus from St. Johns Adminsistration to Pearl St. & Bay St.bus bus
    2. Fly from Jacksonville (JAX) to Key West International Airport (EYW)plane plane JAX - EYW
    9h 12m
    $133–400

  6. Bus to Jacksonville, fly to Miami International Airport, shuttle

    1. Take the bus from St. Johns Adminsistration to Pearl St. & Bay St.bus bus
    2. Fly from Jacksonville (JAX) to Miami International Airport (MIA)plane plane JAX - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus
    10h 8m
    $228–520

  7. Bus

    1. Take the bus from St. Johns Adminsistration to JRTC - Express Selectbus bus
    2. Take the bus from Jacksonville to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to Whitehead & Eatonbus bus Lks
    18h 41m
    $101–166

Orlando Sanford (SFB) to Key West International Airport (EYW) flights

Calendar4Weekly Planes
Duration1h 14mAverage Duration
Ticket$41Cheapest Price
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Comparing Your Travel Options

Map of how to get from Saint Augustine to Key West, FL.ExpandLaunch map view
  • Distance: 384.9 mi
  • Duration: 4h 16m

What companies run services between Saint Augustine, FL, USA and Key West, FL, USA?

You can take a vehicle from Saint Augustine to Whitehead & Eaton via St. Johns Adminsistration, JRTC - Express Select, Jacksonville, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 18h 41m.

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