Rome2Rio

How to get fromSaint Augustine to Mayo Clinicby bus, plane, bus (Flixbus, Greyhound), taxi, train, or car

Find Transport to Mayo Clinic

See all options

There are 7 ways to get from Saint Augustine to Mayo Clinic by bus, plane, bus (Flixbus, Greyhound), taxi, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Jacksonville, fly to Rochester

    best
    1. Take the bus from St. Johns Adminsistration to Pearl St. & Bay St.bus bus
    2. Fly from Jacksonville (JAX) to Rochester (RST)plane plane JAX - RST
    10h 35m
    $134–610

  2. Bus

    1. Take the bus from St. Johns Adminsistration to JRTC - Express Selectbus bus
    2. Take the bus from Jacksonville to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    5. Take the bus from Milwaukee to Rochesterbus bus
    35h 29m
    $260–463

  3. Taxi, train, bus

    1. Take the taxi from Saint Augustine to Jacksonvilletaxi taxi
    2. Take the train from Jacksonville to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochesterbus bus
    47h 11m
    $775–1,548

  4. Drive 1,346.8 mi

    1. Drive from Saint Augustine to Mayo Cliniccar car 1,346.8 mi
    24h 10m
    $246–355

  5. Bus to Jacksonville, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from St. Johns Adminsistration to Pearl St. & Bay St.bus bus
    2. Fly from Jacksonville (JAX) to Minneapolis–Saint Paul International Airport (MSP)plane plane JAX - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 38m
    $215–772

  6. Bus to Orlando, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Jacksonville to Orlando Bus Stationbus bus
    2. Fly from Orlando (MCO) to Minneapolis–Saint Paul International Airport (MSP)plane plane MCO - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    12h 8m
    $327–1,252

  7. Bus, train

    1. Take the bus from St. Johns Adminsistration to JRTC - Express Selectbus bus
    2. Take the train from Jacksonville to Chicago Union Stationtrain train
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    2d
    $588–1,250

Jacksonville (JAX) to Rochester (RST) flights

Calendar46Weekly Planes
Duration6h 57mAverage Duration
Ticket$119Cheapest Price
See schedules

Questions & Answers

Map of how to get from Saint Augustine to Mayo Clinic.ExpandLaunch map view
  • Distance: 1,168.3 mi
  • Duration: 10h 35m

What companies run services between Saint Augustine, FL, USA and Mayo Clinic, MN, USA?

You can take a vehicle from Saint Augustine to Mayo Clinic via St. Johns Adminsistration, JRTC - Express Select, Jacksonville, Atlanta Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 35h 29m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound