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How to get fromSaint Augustine to Santeeby taxi, train, car, bus, plane, or bus (Flixbus, Greyhound)

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There are 5 ways to get from Saint Augustine to Santee by taxi, train, car, bus, plane, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, train, drive (Amtrak)

    best
    1. Take the taxi from Saint Augustine to Jacksonvilletaxi taxi
    2. Take the train from Jacksonville to Charleston Amtrak Stationtrain train
    3. Drive from Charleston Amtrak Station to Santeecar car
    6h 11m
    $202–324

  2. Drive 277.4 mi

    cheapest
    1. Drive from Saint Augustine to Santeecar car 277.4 mi
    4h 38m
    $51–74

  3. Bus, taxi

    1. Take the bus from St. Johns Adminsistration to JRTC - Express Selectbus bus
    2. Take the bus from Jacksonville to Walterboro, SCbus bus
    3. Take the taxi from Walterboro, SC to Santeetaxi taxi
    6h 42m
    $142–202

  4. Bus, fly, drive

    1. Take the bus from St. Johns Adminsistration to Pearl St. & Bay St.bus bus
    2. Fly from Jacksonville (JAX) to Columbia (CAE)plane plane JAX - CAE
    3. Drive from Columbia-Airport-CAE to Santeecar car
    8h 2m
    $183–986

  5. Bus

    1. Take the bus from St. Johns Adminsistration to JRTC - Express Selectbus bus St. Johns
    2. Take the bus from Jacksonville to Orangeburgbus bus FlixBus 2433
    7h 15m
    $127–187

Jacksonville (JAX) to Columbia (CAE) flights

Calendar84Weekly Planes
Duration4h 39mAverage Duration
Ticket$162Cheapest Price
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Questions & Answers

Map of how to get from Saint Augustine to Santee.ExpandLaunch map view
  • Distance: 348 mi
  • Duration: 6h 11m

What companies run services between Saint Augustine, FL, USA and Santee, SC, USA?

You can take a vehicle from Saint Augustine to Santee via St. Johns Adminsistration, JRTC - Express Select, Jacksonville, and Orangeburg in around 7h 15m.

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Train operators
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