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How to get fromSaint Charles to Indianapolisby train, bus, train (Amtrak), car, plane, bus (Flixbus), or subway

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There are 7 ways to get from Saint Charles to Indianapolis by train, bus, train (Amtrak), car, plane, bus (Flixbus), or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Geneva to Chicago OTCtrain train Up-W
    2. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus Greyhound US0100 / ...
    5h 36m
    $47–80

  2. Drive 209 mi

    cheapest
    1. Drive from Saint Charles to Indianapoliscar car 209 mi
    4h
    $39–56

  3. Train

    1. Take the train from Geneva to Chicago OTCtrain train Up-W
    2. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    7h 20m
    $80–155

  4. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Elgin Transportation Center Bay 4 to Rosemont CTA Stationbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Indianapolis (IND)plane plane ORD - IND
    4h 15m
    $462–1,153

  5. Train, bus via Indianapolis

    1. Take the train from Geneva to Chicago OTCtrain train Up-W
    2. Take the bus from Chicago Bus Station to Indianapolisbus bus FlixBus 2511 / ...
    6h 16m
    $49–75

  6. Bus

    1. Take the bus from Elgin Transportation Center Bay 4 to Rosemont CTA Stationbus bus 603
    2. Take the bus from Chicago Bus Station to Indianapolisbus bus FlixBus 2511 / ...
    7h 12m
    $72–104

  7. Train, subway to Chicago Midway International Airport, fly

    1. Take the train from Geneva to Chicago OTCtrain train
    2. Take the subway from Clark/Lake to Midwaysubway subway
    3. Fly from Chicago Midway International Airport (MDW) to Indianapolis (IND)plane plane MDW - IND
    5h 26m
    $86–519

Chicago O'Hare International Airport (ORD) to Indianapolis (IND) flights

Calendar98Weekly Planes
Duration1h 15mAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

Map of how to get from Saint Charles to Indianapolis.ExpandLaunch map view
  • Distance: 219.2 mi
  • Duration: 5h 36m

What companies run services between Saint Charles, IL, USA and Indianapolis, IN, USA?

You can take a vehicle from Saint Charles to Indianapolis via Geneva, Chicago OTC, Madison & Canal, Clinton & Jackson, and Chicago Union Station in around 7h 20m. Alternatively, you can take a vehicle from Saint Charles to Indianapolis via Elgin Transportation Center Bay 4, Rosemont CTA Station, Rosemont, Jefferson Park, Jefferson Park Transit Center, Washington & Jefferson, and Chicago Bus Station in around 7h 12m.

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