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How to get fromSaint Charles to Ashevilleby plane, car, bus (Greyhound, Flixbus), or bus (Greyhound)

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There are 6 ways to get from Saint Charles to Asheville by plane, car, bus (Greyhound, Flixbus), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Greenville–Spartanburg International Airport, drive

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Greenville–Spartanburg International Airport (GSP)plane plane STL - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Ashevillecar car
    6h 20m
    $135–721

  2. Fly to Asheville Regional Airport

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Asheville Regional Airport (AVL)plane plane STL - AVL
    6h 56m
    $95–485

  3. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    24h 24m
    $156–314

  4. Drive 608.9 mi

    1. Drive from Saint Charles to Ashevillecar car 608.9 mi
    10h 32m
    $112–161

  5. Fly to Mcghee Tyson Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS)plane plane STL - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Ashevillecar car
    8h 24m
    $144–784

  6. Bus via Columbus (Greyhound)

    1. Take the bus from St Louis Bus Station to Columbusbus bus
    2. Take the bus from Columbus to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    25h 36m
    $151–309

Saint Charles to Asheville by bus and train

Calendar7Weekly Services
Duration24h 24mAverage Duration
Ticket$156Cheapest Price
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Questions & Answers

Map of how to get from Saint Charles to Asheville.ExpandLaunch map view
  • Distance: 603.6 mi
  • Duration: 6h 20m

What companies run services between Saint Charles, MO, USA and Asheville, NC, USA?

You can take a bus from Riverport Lane @ Riverport Eb to Asheville, NC via North Hanley Transit Center, NORTH HANLEY station, CIVIC CENTER station, St Louis Bus Station, Atlanta Bus Station, and Winston Salem(Trans Center) in around 24h 24m. Alternatively, Delta, American Airlines, and United Airlines fly from Lambert–St. Louis International Airport (STL) to Asheville Regional Airport (AVL) hourly.

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