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How to get fromSaint Charles to Bostonby plane, bus, train (Amtrak), bus (Greyhound, Flixbus), car, or train

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There are 10 ways to get from Saint Charles to Boston by plane, bus, train (Amtrak), bus (Greyhound, Flixbus), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Manchester Airport, bus

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Manchester Airport (MHT)plane plane STL - MHT
    2. Take the bus from Boston Manchester Airport to Bostonbus bus
    8h 26m
    $126–584

  2. Fly to Theodore Francis Green State Airport, train

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Theodore Francis Green State Airport (PVD)plane plane STL - PVD
    2. Take the train from TF Green Airport to South Stationtrain train
    8h 42m
    $101–426

  3. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the train from Chicago Union Station to Bostontrain train Lake Shore Limited
    29h 52m
    $717–1,159

  4. Bus

    1. Take the bus from St Louis Bus Station to Newark Penn Stationbus bus Greyhound US0421
    2. Take the bus from Newark Penn Station to Bostonbus bus Greyhound US0235 / ...
    32h 51m
    $225–358

  5. Drive  1,164 mi

    1. Drive from Saint Charles to Bostoncar car 1,164 mi
    20h 42m
    $213–307

  6. Fly to Barnstable Municipal Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Barnstable Municipal Airport (HYA)plane plane STL - HYA
    2. Take the bus from Barnstable Airport to Bostonbus bus
    8h 56m
    $170–794

  7. Fly to Worcester Regional Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Worcester Regional Airport (ORH)plane plane STL - ORH
    2. Take the bus from Worcester Union Station to Bostonbus bus
    9h 21m
    $125–586

  8. Fly to Laguardia Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Laguardia Airport (LGA)plane plane STL - LGA
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train
    9h 28m
    $320–776

  9. Fly to Newark Liberty International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Newark Liberty International Airport (EWR)plane plane STL - EWR
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train
    9h 26m
    $449–1,149

  10. Bus via Alewife

    1. Take the bus from St Louis Bus Station to Newark Penn Stationbus bus Greyhound US0421
    2. Take the bus from Newark Penn Station to Cambridgebus bus FlixBus 2619
    33h 58m
    $235–363

Lambert–St. Louis International Airport (STL) to Manchester Airport (MHT) flights

Calendar62Weekly Planes
Duration5h 38mAverage Duration
Ticket$108Cheapest Price
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Comparing Your Travel Options

Map of how to get from Saint Charles to Boston.ExpandLaunch map view
  • Distance: 1,100.6 mi
  • Duration: 8h 26m

What companies run services between Saint Charles, MO, USA and Boston, MA, USA?

You can take a vehicle from Saint Charles to Boston via Riverport Lane @ Riverport Eb, North Hanley Transit Center, NORTH HANLEY station, CIVIC CENTER station, St. Louis, and Chicago Union Station in around 29h 52m. Alternatively, you can take a vehicle from Saint Charles to Boston via 4375 Rider Trail North Sb, North Hanley Transit Center, Civic Center Transit Center, St Louis Bus Station, and Newark Penn Station in around 32h 51m.

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