There are 6 ways to get from Saint Charles to Chicago by bus, plane, train (Amtrak), bus (Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Line 34 bus to Lambert–St. Louis International Airport, fly to Chicago Midway International Airport
best- Take the bus from 4375 Rider Trail North Sb to North Hanley Transit Centerbus
- Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane STL - MDW
3h 30m$56–369Bus (Flixbus)
cheapest- Take the bus from St Louis Bus Station to Chicago Bus Stationbus FlixBus 2510 / ...
8h 38m$47–82Train (Amtrak)
- Take the train from St. Louis to Chicago Union Stationtrain Lincoln Service / ...
6h 44m$94–194Drive 306.3 mi
- Drive from Saint Charles to Chicagocar 306.3 mi
5h 21m$56–81Line 34 bus to Lambert–St. Louis International Airport, fly to Chicago O'Hare International Airport
- Take the bus from 4375 Rider Trail North Sb to North Hanley Transit Centerbus
- Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane STL - ORD
3h 53m$276–709Drive to Decatur Airport, fly to Chicago O'Hare International Airport
- Drive from Saint Charles to Decatur Airport (DEC)car
- Fly from Decatur Airport (DEC) to Chicago O'Hare International Airport (ORD)plane DEC - ORD
4h 36m$57–261
Saint Charles to Chicago by bus and train (Amtrak)
Questions & Answers
The cheapest way to get from Saint Charles to Chicago is to bus which costs $45 - $85 and takes 8h 38m.
The fastest way to get from Saint Charles to Chicago is to line 34 bus and fly which takes 3h 30m and costs $55 - $370.
No, there is no direct bus from Saint Charles to Chicago station. However, there are services departing from 4375 Rider Trail North Sb and arriving at Chicago Bus Station via North Hanley Transit Center and St Louis Bus Station. The journey, including transfers, takes approximately 8h 38m.
No, there is no direct train from Saint Charles station to Chicago station. However, there are services departing from NORTH HANLEY station and arriving at Chicago Union Station via St. Louis. The journey, including transfers, takes approximately 6h 44m.
The distance between Saint Charles and Chicago is 281 miles. The road distance is 308.1 miles.
The best way to get from Saint Charles to Chicago without a car is to train which takes 6h 44m and costs $90 - $200.
It takes approximately 3h 30m to get from Saint Charles to Chicago, including transfers.
Saint Charles to Chicago bus services, operated by Flixbus USA, depart from St Louis Bus Station.
Saint Charles to Chicago train services, operated by Amtrak, depart from St. Louis station.
The best way to get from Saint Charles to Chicago is to train which takes 6h 44m and costs $90 - $200. Alternatively, you can bus, which costs $45 - $85 and takes 8h 38m.
What companies run services between Saint Charles, MO, USA and Chicago, IL, USA?
Amtrak operates a train from St. Louis to Chicago Union Station 5 times a day. Tickets cost $90–190 and the journey takes 4h 55m. Alternatively, Flixbus USA operates a bus from St Louis Bus Station to Chicago Bus Station twice daily. Tickets cost $45–80 and the journey takes 6h 5m.
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $45–310
Flights from Decatur Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $30–220
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $50–360
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $45–310
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $90–190
- Website
- https://www.amtrak.com/home.html
- Phone
- 314-982-1406
- [email protected]
- Website
- metrostlouis.org
Bus from 4375 Rider Trail North Sb to North Hanley Transit Center
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- $1
- Website
- https://www.metrostlouis.org
Bus from 4375 Rider Trail North Sb to North Hanley Transit Center
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- $1
- Website
- https://www.metrostlouis.org
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from St Louis Bus Station to Chicago Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- Twice daily
- Estimated price
- $45–80
- Schedules at
- flixbus.com
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More Questions & Answers
Saint Charles to Chicago bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
Saint Charles to Chicago train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Saint Charles to Chicago is 308 miles. It takes approximately 5h 21m to drive from Saint Charles to Chicago.
There are 1300+ hotels available in Chicago.