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How to get fromSaint Charles to Floridaby bus, plane, bus (Greyhound, Flixbus), or car

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There are 10 ways to get from Saint Charles to Florida by bus, plane, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 34 bus, fly to Jacksonville

    best
    1. Take the bus from 4375 Rider Trail North Sb to North Hanley Transit Centerbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Jacksonville (JAX)plane plane STL - JAX
    5h 29m
    $118–573

  2. Fly to Northwest Florida Beaches International Airport, drive

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Northwest Florida Beaches International Airport (ECP)plane plane STL - ECP
    2. Drive from Northwest Florida Beaches International Airport (ECP) to Tallahasseecar car
    5h 54m
    $110–487

  3. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus Greyhound US0186
    2. Take the bus from Atlanta Bus Station to Jacksonvillebus bus FlixBus N2434 / ...
    21h 23m
    $157–270

  4. Drive  880.9 mi

    1. Drive from Saint Charles to Jacksonvillecar car 880.9 mi
    15h 35m
    $161–233

  5. Fly to Miami International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Miami International Airport (MIA)plane plane STL - MIA
    5h 1m
    $520–923

  6. Fly to Tampa

    1. Fly from Lambert–St. Louis International Airport (STL) to Tampa (TPA)plane plane STL - TPA
    5h 14m
    $129–622

  7. Fly to Fort Lauderdale–Hollywood International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane STL - FLL
    5h 15m
    $519–1,123

  8. Fly to Orlando

    1. Fly from Lambert–St. Louis International Airport (STL) to Orlando (MCO)plane plane STL - MCO
    5h 37m
    $201–345

  9. Line 34 bus, fly to Sarasota–Bradenton International Airport, line 203 bus

    1. Take the bus from 4375 Rider Trail North Sb to North Hanley Transit Centerbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Sarasota–Bradenton International Airport (SRQ)plane plane STL - SRQ
    3. Take the bus from Downtown Station to 34Th St S Nb/1St Av Sbus bus
    6h 45m
    $114–520

  10. Fly to Ft. Myers

    1. Fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW)plane plane STL - RSW
    6h 40m
    $140–675

Lambert–St. Louis International Airport (STL) to Jacksonville (JAX) flights

Calendar55Weekly Planes
Duration3h 36mAverage Duration
Ticket$102Cheapest Price
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Comparing Your Travel Options

Map of how to get from Saint Charles to Florida.ExpandLaunch map view
  • Distance: 792 mi
  • Duration: 5h 29m

What companies run services between Saint Charles, MO, USA and Florida, USA?

You can take a vehicle from Saint Charles to Jacksonville via 4375 Rider Trail North Sb, North Hanley Transit Center, NORTH HANLEY station, CIVIC CENTER station, St Louis Bus Station, and Atlanta Bus Station in around 21h 23m. Alternatively, American Airlines and Southwest Airlines fly from Lambert–St. Louis International Airport (STL) to Miami International Airport (MIA) 5 times a day.

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