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How to get fromSaint Charles to Floridaby bus, plane, bus (Greyhound, Flixbus), or car

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There are 10 ways to get from Saint Charles to Florida by bus, plane, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 34 bus, fly to Jacksonville

    best
    1. Take the bus from 4375 Rider Trail North Sb to North Hanley Transit Centerbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Jacksonville (JAX)plane plane STL - JAX
    5h 16m
    $115–607

  2. Fly to Northwest Florida Beaches International Airport, drive

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Northwest Florida Beaches International Airport (ECP)plane plane STL - ECP
    2. Drive from Northwest Florida Beaches International Airport (ECP) to Tallahasseecar car
    5h 47m
    $112–511

  3. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus Greyhound US0186
    2. Take the bus from Atlanta Bus Station to Jacksonvillebus bus FlixBus N2434 / ...
    21h 16m
    $149–294

  4. Drive 880.9 mi

    1. Drive from Saint Charles to Jacksonvillecar car 880.9 mi
    15h 35m
    $161–233

  5. Fly to Fort Lauderdale–Hollywood International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane STL - FLL
    5h 4m
    $556–1,107

  6. Fly to Miami International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Miami International Airport (MIA)plane plane STL - MIA
    4h 58m
    $127–607

  7. Fly to Tampa

    1. Fly from Lambert–St. Louis International Airport (STL) to Tampa (TPA)plane plane STL - TPA
    5h 19m
    $426–2,006

  8. Fly to Orlando

    1. Fly from Lambert–St. Louis International Airport (STL) to Orlando (MCO)plane plane STL - MCO
    5h 28m
    $188–499

  9. Fly to Ft. Myers

    1. Fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW)plane plane STL - RSW
    6h 37m
    $127–609

  10. Line 34 bus, fly to Sarasota–Bradenton International Airport, line 203 bus

    1. Take the bus from 4375 Rider Trail North Sb to North Hanley Transit Centerbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Sarasota–Bradenton International Airport (SRQ)plane plane STL - SRQ
    3. Take the bus from Downtown Station to 34Th St S Nb/1St Av Sbus bus
    6h 56m
    $156–764

Saint Charles to Florida by bus and train

Calendar12Weekly Services
Duration21h 16mAverage Duration
Ticket$149Cheapest Price
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Questions & Answers

Map of how to get from Saint Charles to Florida.ExpandLaunch map view
  • Distance: 787.6 mi
  • Duration: 5h 16m

What companies run services between Saint Charles, MO, USA and Florida, USA?

You can take a bus from 4375 Rider Trail North Sb to Jacksonville via North Hanley Transit Center, NORTH HANLEY station, CIVIC CENTER station, St Louis Bus Station, and Atlanta Bus Station in around 21h 16m. Alternatively, Southwest Airlines and Delta fly from Lambert–St. Louis International Airport (STL) to Fort Lauderdale–Hollywood International Airport (FLL) every 4 hours.

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