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How to get fromSaint Charles to Fort Myersby plane, bus (Greyhound, Flixbus), car, bus, train, or taxi

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There are 7 ways to get from Saint Charles to Fort Myers by plane, bus (Greyhound, Flixbus), car, bus, train, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Lambert–St. Louis International Airport to Ft. Myers

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW)plane plane STL - RSW
    6h 11m
    $137–659

  2. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to University of South Floridabus bus
    3. Take the bus from Tampa USF to Fort Myersbus bus
    24h 28m
    $207–381

  3. Drive 1,127.6 mi

    1. Drive from Saint Charles to Fort Myerscar car 1,127.6 mi
    19h 24m
    $206–298

  4. Fly Lambert–St. Louis International Airport to Sarasota–Bradenton International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Sarasota–Bradenton International Airport (SRQ)plane plane STL - SRQ
    2. Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus bus
    7h 37m
    $177–827

  5. Train to Midamerica St. Louis Airport, fly to Punta Gorda Airport, taxi

    1. Take the train from NORTH HANLEY station to SHILOH-SCOTT stationtrain train
    2. Fly from Midamerica St. Louis Airport (BLV) to Punta Gorda Airport (PGD)plane plane BLV - PGD
    3. Take the taxi from Punta Gorda Airport (PGD) to Fort Myerstaxi taxi
    5h 59m
    $197–557

  6. Fly Lambert–St. Louis International Airport to Tampa, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Tampa (TPA)plane plane STL - TPA
    2. Take the bus from Tampa Airport to Fort Myersbus bus
    7h 28m
    $472–2,091

  7. Fly Lambert–St. Louis International Airport to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane STL - FLL
    2. Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus bus
    7h 48m
    $525–1,139

Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW) flights

Calendar62Weekly Planes
Duration3h 58mAverage Duration
Ticket$133Cheapest Price
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Questions & Answers

Map of how to get from Saint Charles to Fort Myers.ExpandLaunch map view
  • Distance: 1,011.3 mi
  • Duration: 6h 11m

What companies run services between Saint Charles, MO, USA and Fort Myers, FL, USA?

Southwest Airlines, Delta, and American Airlines fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW) every 3 hours. Alternatively, you can take a bus from Riverport Lane @ Riverport Eb to Fort Myers via North Hanley Transit Center, NORTH HANLEY station, CIVIC CENTER station, St Louis Bus Station, Atlanta Bus Station, Tampa USF, and Fort Myers in around 24h 28m.

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