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How to get fromSaint Charles to Jacksonvilleby bus, plane, bus (Greyhound, Flixbus), or car

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There are 4 ways to get from Saint Charles to Jacksonville by bus, plane, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 34 bus, fly to Jacksonville

    best
    1. Take the bus from 4375 Rider Trail North Sb to North Hanley Transit Centerbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Jacksonville (JAX)plane plane STL - JAX
    5h 29m
    $118–573

  2. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus Greyhound US0186
    2. Take the bus from Atlanta Bus Station to Jacksonvillebus bus FlixBus N2434 / ...
    21h 23m
    $157–270

  3. Drive  880.9 mi

    1. Drive from Saint Charles to Jacksonvillecar car 880.9 mi
    15h 35m
    $161–233

  4. Fly to Brunswick Golden Isles Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Brunswick Golden Isles Airport (BQK)plane plane STL - BQK
    2. Take the bus from Brunswick to Jacksonvillebus bus
    7h 59m
    $127–515

Lambert–St. Louis International Airport (STL) to Jacksonville (JAX) flights

Calendar57Weekly Planes
Duration3h 36mAverage Duration
Ticket$102Cheapest Price
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Comparing Your Travel Options

Map of how to get from Saint Charles to Jacksonville.ExpandLaunch map view
  • Distance: 792 mi
  • Duration: 5h 29m

What companies run services between Saint Charles, MO, USA and Jacksonville, FL, USA?

You can take a vehicle from Saint Charles to Jacksonville via 4375 Rider Trail North Sb, North Hanley Transit Center, NORTH HANLEY station, CIVIC CENTER station, St Louis Bus Station, and Atlanta Bus Station in around 21h 23m.

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