There are 9 ways to get from Saint Charles to Kalamazoo by train (Amtrak), bus (Flixbus, Amtrak), car, plane, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from St. Louis to Chicago Union Stationtrain Lincoln Service / ...
- Take the train from Chicago Union Station to Kalamazootrain Wolverine / ...
9h 56m$122–289Drive 421.9 mi
cheapest- Drive from Saint Charles to Kalamazoocar 421.9 mi
7h 18m$77–112Bus
- Take the bus from St Louis Bus Station to Chicago Bus Stationbus FlixBus N2521 / ...
- Take the bus from Chicago Union Station to Kalamazoobus Amtrak Thruway Connecting Service
12h 1m$90–143Fly to Kalamazoo-Battle Creek International Airport
- Fly from Lambert–St. Louis International Airport (STL) to Kalamazoo-Battle Creek International Airport (AZO)plane STL - AZO
6h 42m$79–402Train, bus
- Take the train from St. Louis to Chicago Union Stationtrain Lincoln Service / ...
- Take the bus from Chicago Bus Station to Kalamazoo Bus Stopbus Greyhound US0160
11h 7m$110–240Fly to Chicago Midway International Airport, train
- Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane STL - MDW
- Take the train from Chicago Union Station to Kalamazootrain
6h 54m$104–455Fly to Chicago O'Hare International Airport, train
- Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane STL - ORD
- Take the train from Chicago Union Station to Kalamazootrain
7h 24m$377–818Fly to Gerald R. Ford International Airport, bus
- Fly from Lambert–St. Louis International Airport (STL) to Gerald R. Ford International Airport (GRR)plane STL - GRR
- Take the bus from Grand Rapids to Kalamazoo Metro Transitbus
8h 58m$91–428Fly to Detroit, train
- Fly from Lambert–St. Louis International Airport (STL) to Detroit (DTW)plane STL - DTW
- Take the train from Dearborn to Kalamazootrain
7h 44m$699–1,057
Lambert–St. Louis International Airport (STL) to Kalamazoo-Battle Creek International Airport (AZO) flights
Comparing Your Travel Options
The cheapest way to get from Saint Charles to Kalamazoo is to drive which costs $75 - $120 and takes 7h 18m.
The fastest way to get from Saint Charles to Kalamazoo is to fly which takes 6h 42m and costs $75 - $410.
No, there is no direct bus from Saint Charles to Kalamazoo. However, there are services departing from 4375 Rider Trail North Sb and arriving at Kalamazoo via North Hanley Transit Center, St Louis Bus Station and Chicago Union Station. The journey, including transfers, takes approximately 12h 1m.
No, there is no direct train from Saint Charles station to Kalamazoo. However, there are services departing from NORTH HANLEY station and arriving at Kalamazoo via St. Louis and Chicago Union Station. The journey, including transfers, takes approximately 9h 56m.
The distance between Saint Charles and Kalamazoo is 444 miles. The road distance is 424.4 miles.
The best way to get from Saint Charles to Kalamazoo without a car is to train which takes 9h 56m and costs $120 - $290.
It takes approximately 9h 56m to get from Saint Charles to Kalamazoo, including transfers.
Saint Charles to Kalamazoo bus services, operated by Flixbus USA, depart from St Louis Bus Station.
Saint Charles to Kalamazoo train services, operated by Amtrak, depart from St. Louis station.
The best way to get from Saint Charles to Kalamazoo is to train which takes 9h 56m and costs $120 - $290. Alternatively, you can bus, which costs $90 - $150 and takes 12h 1m, you could also fly, which costs $75 - $410 and takes 6h 42m.
What companies run services between Saint Charles, MO, USA and Kalamazoo, MI, USA?
You can take a vehicle from Saint Charles to Kalamazoo via Riverport Lane @ Riverport Eb, North Hanley Transit Center, NORTH HANLEY station, CIVIC CENTER station, St. Louis, and Chicago Union Station in around 9h 56m. Alternatively, you can take a vehicle from Saint Charles to Kalamazoo via 4375 Rider Trail North Sb, North Hanley Transit Center, Civic Center Transit Center, St Louis Bus Station, Chicago Bus Station, and Chicago Union Station in around 12h 1m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- $50–340
Flights from Lambert–St. Louis International Airport to Gerald R. Ford International Airport via Chicago Midway International Airport
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $60–380
Flights from Lambert–St. Louis International Airport to Gerald R. Ford International Airport via Baltimore
- Ave. Duration
- 4h 57m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–600
Flights from Lambert–St. Louis International Airport to Detroit
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $85–550
Flights from Lambert–St. Louis International Airport to Detroit via Chicago Midway International Airport
- Ave. Duration
- 3h 15m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $90–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $70–180
- Website
- Amtrak
Train from Chicago Union Station to Kalamazoo
- Ave. Duration
- 2h 6m
- Frequency
- 4 times a day
- Estimated price
- $35–90
- Website
- Amtrak
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $70–180
- Website
- Amtrak
Train from Chicago Union Station to Kalamazoo
- Ave. Duration
- 2h 6m
- Frequency
- 4 times a day
- Estimated price
- $35–90
- Website
- Amtrak
Train from Chicago Union Station to Kalamazoo
- Ave. Duration
- 2h 6m
- Frequency
- 4 times a day
- Estimated price
- $35–90
- Website
- Amtrak
Train from Dearborn to Kalamazoo
- Ave. Duration
- 2h 29m
- Frequency
- 3 times a day
- Estimated price
- $30–85
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Chicago Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- Twice daily
- Estimated price
- $45–75
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Saint Charles to Kalamazoo bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
Kalamazoo is 1h ahead of Saint Charles. It is currently 4:20 AM in Saint Charles and 5:20 AM in Kalamazoo.
Saint Charles to Kalamazoo train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Saint Charles to Kalamazoo is 424 miles. It takes approximately 7h 18m to drive from Saint Charles to Kalamazoo.
There are 52+ hotels available in Kalamazoo.







