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How to get fromSaint Charles to Kirksvilleby bus, train, train (Amtrak), car, or shuttle

Find Transport to Kirksville

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There are 4 ways to get from Saint Charles to Kirksville by bus, train, train (Amtrak), car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus Greyhound US0180s / ...
    2. Take the train from Kansas City to La Plata Stationtrain train Southwest Chief
    10h 35m
    $122–227

  2. Shuttle

    cheapest
    1. Take a shuttle bus from St. Louis to Bowling Green, Moshuttle bus
    2. Take a shuttle bus from Bowling Green, Mo to Columbiashuttle bus
    3. Take a shuttle bus from Columbia to Hy-Vee - Kirksvilleshuttle bus
    7h 25m
    $12–19

  3. Train (Amtrak)

    1. Take the train from St. Louis to Kansas Citytrain train Missouri River Runner / ...
    2. Take the train from Kansas City to La Plata Stationtrain train Southwest Chief
    10h 49m
    $179–344

  4. Drive 185.7 mi

    1. Drive from Saint Charles to Kirksvillecar car 185.7 mi
    3h 24m
    $34–49

Questions & Answers

Map of how to get from Saint Charles to Kirksville.ExpandLaunch map view
  • Distance: 425.2 mi
  • Duration: 10h 35m

What companies run services between Saint Charles, MO, USA and Kirksville, MO, USA?

You can take a bus from Riverport Lane @ Riverport Eb to Kirksville via North Hanley Transit Center, NORTH HANLEY station, CIVIC CENTER station, St. Louis, Kansas City, and La Plata Station in around 10h 49m. Alternatively, you can take a bus from 4375 Rider Trail North Sb to Hy-Vee - Kirksville via North Hanley Transit Center, St. Louis, Bowling Green, Mo, and Columbia in around 7h 25m.

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