What is the cheapest way to get from Saint Charles to Knoxville?

The cheapest way to get from Saint Charles to Knoxville is to drive which costs $90 - $140 and takes 8h 22m.

What is the fastest way to get from Saint Charles to Knoxville?

The fastest way to get from Saint Charles to Knoxville is to fly and drive which takes 5h 42m and costs $110 - $700.

Is there a direct bus between Saint Charles and Knoxville?

No, there is no direct bus from Saint Charles to Knoxville. However, there are services departing from 4375 Rider Trail North Sb and arriving at Knoxville, TN via St Louis Bus Station and New York, NY. The journey, including transfers, takes approximately 40h 5m.

How far is it from Saint Charles to Knoxville?

The distance between Saint Charles and Knoxville is 437 miles. The road distance is 505.6 miles.

How do I travel from Saint Charles to Knoxville without a car?

The best way to get from Saint Charles to Knoxville without a car is to bus which takes 40h 5m and costs $290 - $470.

How long does it take to get from Saint Charles to Knoxville?

It takes approximately 5h 59m to get from Saint Charles to Knoxville, including transfers.

Where do I catch the Saint Charles to Knoxville bus from?

Saint Charles to Knoxville bus services, operated by Greyhound USA, depart from St Louis Bus Station.

Bus or fly from Saint Charles to Knoxville?

The best way to get from Saint Charles to Knoxville is to fly which takes 5h 59m and costs $170 - $850. Alternatively, you can bus, which costs $290 - $470 and takes 40h 5m.

Where does the Saint Charles to Knoxville bus arrive?

Saint Charles to Knoxville bus services, operated by Greyhound USA, arrive at Newark Penn Station.

What is the time difference between Saint Charles and Knoxville?

Knoxville is 1h ahead of Saint Charles. It is currently 10:12 PM in Saint Charles and 11:12 PM in Knoxville.

Can I drive from Saint Charles to Knoxville?

Yes, the driving distance between Saint Charles to Knoxville is 506 miles. It takes approximately 8h 22m to drive from Saint Charles to Knoxville.

Where can I stay near Knoxville?

There are 317+ hotels available in Knoxville.

Saint Charles to Knoxville - 6 ways to travel via plane, bus, and car

How to get fromSaint Charles to Knoxville

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There are 6 ways to get from Saint Charles to Knoxville by plane, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly to Mcghee Tyson Airport
best
1. Fly from Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS)plane STL - TYS
5h 59m
$179–824
Drive 502.7 mi
cheapest
1. Drive from Saint Charles to Knoxvillecar 502.7 mi
8h 22m
$92–133
Bus
1. Take the bus from St Louis Bus Station to Newark Penn Stationbus Greyhound US0421
2. Take the bus from New York, NY to Knoxville, TNbus Ny
40h 5m
$294–468
Fly to Nashville, drive
1. Fly from Lambert–St. Louis International Airport (STL) to Nashville (BNA)plane STL - BNA
2. Drive from Nashville-Airport-BNA to Knoxvillecar
5h 42m
$114–654
Fly to Chattanooga Metropolitan Airport, drive
1. Fly from Lambert–St. Louis International Airport (STL) to Chattanooga Metropolitan Airport (CHA)plane STL - CHA
2. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar
7h 9m
$182–932
Bus via Farragut
1. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus Greyhound US0421
2. Take the bus from New York to Knoxvillebus Nyc
40h 28m
$347–567

Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS) flights

113Weekly Planes

5h 2mAverage Duration

$128Cheapest Price

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Questions & Answers

Map of how to get from Saint Charles to Knoxville.

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Distance: 434 mi
Duration: 5h 59m

What companies run services between Saint Charles, MO, USA and Knoxville, TN, USA?

Delta, American Airlines, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS) hourly. Alternatively, you can take a bus from 4375 Rider Trail North Sb to Knoxville via North Hanley Transit Center, NORTH HANLEY station, CIVIC CENTER station, St Louis Bus Station, Newark, Penn Station, Newark Penn Station, Penn Station, 34 St-Herald Sq, East Broadway, New York, NY, and Knoxville, TN in around 40h 5m.

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How to get fromSaint Charles to Knoxvilleby plane, bus (Greyhound), or car

There are 6 ways to get from Saint Charles to Knoxville by plane, bus (Greyhound), or car

Fly to Mcghee Tyson Airport

Drive 502.7 mi

Bus

Fly to Nashville, drive

Fly to Chattanooga Metropolitan Airport, drive

Bus via Farragut