There are 4 ways to get from Saint Charles to Lawrence by bus (Greyhound), train (Amtrak), car, bus, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from St Louis Bus Station to Lawrence Bus Stopbus Greyhound US0180s
8h 38m$72–105Drive 266.8 mi
cheapest- Drive from Saint Charles to Lawrencecar 266.8 mi
4h 31m$49–71Train (Amtrak)
- Take the train from St. Louis to Kansas Citytrain Missouri River Runner / ...
- Take the train from Kansas City to Lawrence Amtrak Stationtrain Southwest Chief
9h 43m$189–294Line 34 bus, fly, train
- Take the bus from 4375 Rider Trail North Sb to North Hanley Transit Centerbus
- Fly from Lambert–St. Louis International Airport (STL) to Kansas City (MCI)plane STL - MCI
- Take the train from Kansas City to Lawrence Amtrak Stationtrain
7h 18m$739–1,055
Lambert–St. Louis International Airport (STL) to Kansas City (MCI) flights
Comparing Your Travel Options
The cheapest way to get from Saint Charles to Lawrence is to drive which costs $45 - $75 and takes 4h 31m.
The fastest way to get from Saint Charles to Lawrence is to drive which takes 4h 31m and costs $45 - $75.
No, there is no direct bus from Saint Charles to Lawrence. However, there are services departing from 4375 Rider Trail North Sb and arriving at Lawrence Bus Stop via St Louis Bus Station. The journey, including transfers, takes approximately 8h 38m.
No, there is no direct train from Saint Charles station to Lawrence station. However, there are services departing from NORTH HANLEY station and arriving at Lawrence Amtrak Station via St. Louis and Kansas City. The journey, including transfers, takes approximately 9h 43m.
The distance between Saint Charles and Lawrence is 351 miles. The road distance is 268.4 miles.
The best way to get from Saint Charles to Lawrence without a car is to bus which takes 8h 38m and costs $70 - $110.
It takes approximately 8h 38m to get from Saint Charles to Lawrence, including transfers.
Saint Charles to Lawrence bus services, operated by Greyhound USA, depart from St Louis Bus Station.
Saint Charles to Lawrence train services, operated by Amtrak, depart from St. Louis station.
The best way to get from Saint Charles to Lawrence is to bus which takes 8h 38m and costs $70 - $110. Alternatively, you can train, which costs $180 - $300 and takes 9h 43m.
What companies run services between Saint Charles, MO, USA and Lawrence, KS, USA?
Greyhound USA operates a bus from St Louis Bus Station to Lawrence Bus Stop once daily. Tickets cost $55–85 and the journey takes 6h 30m. Alternatively, you can take a vehicle from Saint Charles to Lawrence Amtrak Station via Riverport Lane @ Riverport Eb, North Hanley Transit Center, NORTH HANLEY station, CIVIC CENTER station, St. Louis, and Kansas City in around 9h 43m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Kansas City
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $75–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Louis to Kansas City
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $150–240
- Website
- Amtrak
Train from Kansas City to Lawrence Amtrak Station
- Ave. Duration
- 1h 8m
- Frequency
- Once daily
- Estimated price
- $22–35
- Website
- Amtrak
Train from Kansas City to Lawrence Amtrak Station
- Ave. Duration
- 1h 8m
- Frequency
- Once daily
- Estimated price
- $22–35
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Lawrence Bus Stop
- Ave. Duration
- 6h 30m
- Frequency
- Once daily
- Estimated price
- $55–85
- Website
- Greyhound
- Phone
- 314-982-1406
- [email protected]
- Website
- Metro St Louis
Bus from 4375 Rider Trail North Sb to North Hanley Transit Center
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- $1
- Website
- Metro St Louis
Want to know more about travelling around United States
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Booking & Getting There
Saint Charles to Lawrence bus services, operated by Greyhound USA, arrive at Lawrence Bus Stop station.
Saint Charles to Lawrence train services, operated by Amtrak, arrive at Kansas City station.
Yes, the driving distance between Saint Charles to Lawrence is 268 miles. It takes approximately 4h 31m to drive from Saint Charles to Lawrence.
There are 46+ hotels available in Lawrence.








