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How to get fromSaint Charles to Manhattanby plane, bus (Greyhound), car, train, or bus

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There are 9 ways to get from Saint Charles to Manhattan by plane, bus (Greyhound), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Laguardia Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Laguardia Airport (LGA)plane plane STL - LGA
    4h 56m
    $190–573

  2. Fly to John F. Kennedy International Airport

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to John F. Kennedy International Airport (JFK)plane plane STL - JFK
    6h 44m
    $106–428

  3. Bus (Greyhound)

    1. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus Greyhound US0421
    26h 53m
    $197–300

  4. Drive  960.7 mi

    1. Drive from Saint Charles to Manhattancar car 960.7 mi
    16h 52m
    $176–254

  5. Fly to Newark Liberty International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Newark Liberty International Airport (EWR)plane plane STL - EWR
    4h 57m
    $229–949

  6. Fly to Philadelphia International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Philadelphia International Airport (PHL)plane plane STL - PHL
    2. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    6h 21m
    $159–1,374

  7. Fly to Westchester County Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Westchester County Airport (HPN)plane plane STL - HPN
    8h 30m
    $148–687

  8. Fly to Long Island Mac Arthur Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Long Island Mac Arthur Airport (ISP)plane plane STL - ISP
    2. Take the train from Central Islip to New York Penn Stationtrain train
    8h 10m
    $142–601

  9. Bus, train

    1. Take the bus from St Louis Bus Station to Pittsburgh Intermodal Stationbus bus Greyhound US0421
    2. Take the train from Pittsburgh Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Pennsylvanian
    26h 55m
    $357–559

Lambert–St. Louis International Airport (STL) to Laguardia Airport (LGA) flights

Calendar81Weekly Planes
Duration2h 44mAverage Duration
Ticket$136Cheapest Price
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Comparing Your Travel Options

Map of how to get from Saint Charles to Manhattan.ExpandLaunch map view
  • Distance: 914.4 mi
  • Duration: 4h 56m

What companies run services between Saint Charles, MO, USA and Manhattan, NY, USA?

American Airlines, Delta, and Southwest Airlines fly from Lambert–St. Louis International Airport (STL) to Laguardia Airport (LGA) every 2 hours. Alternatively, Greyhound USA operates a bus from St Louis Bus Station to Port Authority Bus Terminal 3 times a day. Tickets cost $180–280 and the journey takes 24h 45m.

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