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How to get fromSaint Charles to Manhattanby bus (Greyhound), train, bus, car, or plane

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There are 5 ways to get from Saint Charles to Manhattan by bus (Greyhound), train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from St Louis Bus Station to Manhattan KSbus bus Greyhound US0180s
    10h 16m
    $64–124

  2. Train, bus

    1. Take the train from St. Louis to Kansas Citytrain train Missouri River Runner / ...
    2. Take the bus from Kansas City Bus Station to Manhattan KSbus bus Greyhound US0180s
    12h 53m
    $112–239

  3. Drive 346.4 mi

    1. Drive from Saint Charles to Manhattancar car 346.4 mi
    5h 49m
    $64–92

  4. Fly to Manhattan Regional Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Manhattan Regional Airport (MHK)plane plane STL - MHK
    6h 14m
    $134–594

  5. Fly to Salina Municipal Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Salina Municipal Airport (SLN)plane plane STL - SLN
    2. Take the bus from Salina to Manhattan KSbus bus
    9h 41m
    $126–589

Saint Charles to Manhattan by bus and train (Greyhound)

Calendar14Weekly Services
Duration10h 16mAverage Duration
Ticket$64Cheapest Price
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Questions & Answers

Map of how to get from Saint Charles to Manhattan.ExpandLaunch map view
  • Distance: 427.1 mi
  • Duration: 10h 16m

What companies run services between Saint Charles, MO, USA and Manhattan, KS, USA?

Greyhound USA operates a bus from St Louis Bus Station to Manhattan KS twice daily. Tickets cost $60–120 and the journey takes 8h 15m. Alternatively, American Airlines and United Airlines fly from Lambert–St. Louis International Airport (STL) to Manhattan Regional Airport (MHK) every 4 hours.

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