Rome2Rio

How to get fromSaint Charles to Memphisby bus (Greyhound, Flixbus), car, plane, or bus

Find Transport to Memphis

See all options

There are 4 ways to get from Saint Charles to Memphis by bus (Greyhound, Flixbus), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus Greyhound US1173
    9h 31m
    $61–99

  2. Drive  295.2 mi

    cheapest
    1. Drive from Saint Charles to Memphiscar car 295.2 mi
    4h 46m
    $51–73

  3. Fly to Memphis

    1. Fly from Lambert–St. Louis International Airport (STL) to Memphis (MEM)plane plane STL - MEM
    7h 15m
    $158–871

  4. Fly to Jonesboro Municipal Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Jonesboro Municipal Airport (JBR)plane plane STL - JBR
    2. Take the bus from Jonesboro to Memphis Bus Stationbus bus
    7h 19m
    $170–523

Lambert–St. Louis International Airport (STL) to Memphis (MEM) flights

Calendar126Weekly Planes
Duration5h 13mAverage Duration
Ticket$142Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Saint Charles to Memphis.ExpandLaunch map view
  • Distance: 332.1 mi
  • Duration: 9h 31m

What companies run services between Saint Charles, MO, USA and Memphis, TN, USA?

Greyhound USA operates a bus from St Louis Bus Station to Memphis Bus Station twice daily. Tickets cost $50–80 and the journey takes 5h 30m. Flixbus USA also services this route once daily. Alternatively, Delta, Southwest Airlines, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Memphis (MEM) hourly.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There