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How to get fromSaint Charles to Memphisby bus (Flixbus, Greyhound), car, plane, or bus

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There are 4 ways to get from Saint Charles to Memphis by bus (Flixbus, Greyhound), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus FlixBus 2510
    8h 13m
    $50–95

  2. Drive 295.2 mi

    1. Drive from Saint Charles to Memphiscar car 295.2 mi
    4h 46m
    $54–78

  3. Fly to Memphis

    1. Fly from Lambert–St. Louis International Airport (STL) to Memphis (MEM)plane plane STL - MEM
    6h 19m
    $135–755

  4. Fly to Jonesboro Municipal Airport, bus, line 04 bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Jonesboro Municipal Airport (JBR)plane plane STL - JBR
    2. Take the bus from Jonesboro to Memphis Bus Stationbus bus
    3. Take the bus from Airways Transit Center to 3RD STREET at EXCHANGE AVENUEbus bus
    7h 21m
    $165–529

Saint Charles to Memphis by bus and train

Calendar14Weekly Services
Duration8h 13mAverage Duration
Ticket$50Cheapest Price
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Questions & Answers

Map of how to get from Saint Charles to Memphis.ExpandLaunch map view
  • Distance: 328.5 mi
  • Duration: 8h 13m

What companies run services between Saint Charles, MO, USA and Memphis, TN, USA?

Flixbus USA operates a bus from St Louis Bus Station to Memphis Bus Station once daily. Tickets cost $45–80 and the journey takes 4h 45m. Greyhound USA also services this route once daily. Alternatively, Southwest Airlines, Delta, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Memphis (MEM) hourly.

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Bus operators

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