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How to get fromSaint Charles to Memphisby bus (Greyhound, Flixbus), car, plane, or bus

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There are 4 ways to get from Saint Charles to Memphis by bus (Greyhound, Flixbus), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from St Louis Bus Station to Memphis Bus Stationbus bus Greyhound US1173
    8h 58m
    $45–85

  2. Drive 295.2 mi

    1. Drive from Saint Charles to Memphiscar car 295.2 mi
    4h 46m
    $54–78

  3. Fly to Memphis

    1. Fly from Lambert–St. Louis International Airport (STL) to Memphis (MEM)plane plane STL - MEM
    6h 20m
    $125–755

  4. Fly to Jonesboro Municipal Airport, bus, line 04 bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Jonesboro Municipal Airport (JBR)plane plane STL - JBR
    2. Take the bus from Jonesboro to Memphis Bus Stationbus bus
    3. Take the bus from Airways Transit Center to 3RD STREET at EXCHANGE AVENUEbus bus
    7h 22m
    $153–517

Saint Charles to Memphis by bus and train

Calendar12Weekly Services
Duration8h 58mAverage Duration
Ticket$45Cheapest Price
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Questions & Answers

Map of how to get from Saint Charles to Memphis.ExpandLaunch map view
  • Distance: 329.9 mi
  • Duration: 8h 58m

What companies run services between Saint Charles, MO, USA and Memphis, TN, USA?

Greyhound USA operates a bus from St Louis Bus Station to Memphis Bus Station once daily. Tickets cost $40–80 and the journey takes 5h 30m. Flixbus USA also services this route 5 times a week. Alternatively, Southwest Airlines, Delta, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Memphis (MEM) hourly.

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