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How to get fromSaint Charles to Milwaukeeby bus, plane, train (Amtrak), bus (Flixbus, Greyhound), or car

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There are 5 ways to get from Saint Charles to Milwaukee by bus, plane, train (Amtrak), bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 34 bus, fly to General Mitchell International Airport

    best
    1. Take the bus from 4375 Rider Trail North Sb to North Hanley Transit Centerbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE)plane plane STL - MKE
    3h 30m
    $487–857

  2. Bus

    cheapest
    1. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus 2510 / ...
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus Greyhound US0150 / ...
    11h 18m
    $66–114

  3. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the train from Chicago Union Station to Milwaukeetrain train Hiawatha Service / ...
    9h 13m
    $121–254

  4. Drive 382.5 mi

    1. Drive from Saint Charles to Milwaukeecar car 382.5 mi
    6h 39m
    $70–101

  5. Fly to Chicago O'Hare International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane plane STL - ORD
    2. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    5h 38m
    $288–733

Saint Charles to Milwaukee by bus and train (Amtrak)

Calendar38Weekly Services
Duration9h 13mAverage Duration
Ticket$121Cheapest Price
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Questions & Answers

Map of how to get from Saint Charles to Milwaukee.ExpandLaunch map view
  • Distance: 341 mi
  • Duration: 3h 30m

What companies run services between Saint Charles, MO, USA and Milwaukee, WI, USA?

You can take a bus from Riverport Lane @ Riverport Eb to Milwaukee via North Hanley Transit Center, NORTH HANLEY station, CIVIC CENTER station, St. Louis, and Chicago Union Station in around 9h 13m. Alternatively, you can take a bus from 4375 Rider Trail North Sb to Milwaukee Intermodal Station via North Hanley Transit Center, Civic Center Transit Center, St Louis Bus Station, and Chicago Bus Station in around 11h 18m.

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