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How to get fromSaint Charles to Milwaukeeby taxi, bus, plane, train (Amtrak), bus (Flixbus, Greyhound), or car

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There are 5 ways to get from Saint Charles to Milwaukee by taxi, bus, plane, train (Amtrak), bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, line 34 bus, fly to General Mitchell International Airport

    best
    1. Take the taxi from Saint Charles to 4375 Rider Trail North Sbtaxi taxi
    2. Take the bus from 4375 Rider Trail North Sb to North Hanley Transit Centerbus bus
    3. Fly from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE)plane plane STL - MKE
    3h 43m
    $500–873

  2. Drive  382.5 mi

    cheapest
    1. Drive from Saint Charles to Milwaukeecar car 382.5 mi
    6h 39m
    $70–101

  3. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the train from Chicago Union Station to Milwaukeetrain train Hiawatha Service / ...
    9h 19m
    $212–334

  4. Bus

    1. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus N2521 / ...
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus Greyhound US0150
    11h 26m
    $78–117

  5. Fly to Chicago O'Hare International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane plane STL - ORD
    2. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    5h 48m
    $303–746

Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE) flights

Calendar15Weekly Planes
Duration1h 38mAverage Duration
Ticket$82Cheapest Price
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Comparing Your Travel Options

Map of how to get from Saint Charles to Milwaukee.ExpandLaunch map view
  • Distance: 345.4 mi
  • Duration: 3h 43m

What companies run services between Saint Charles, MO, USA and Milwaukee, WI, USA?

You can take a vehicle from Saint Charles to Milwaukee via Riverport Lane @ Riverport Eb, North Hanley Transit Center, NORTH HANLEY station, CIVIC CENTER station, St. Louis, and Chicago Union Station in around 9h 19m. Alternatively, you can take a vehicle from Saint Charles to Milwaukee Intermodal Station via 4375 Rider Trail North Sb, North Hanley Transit Center, Civic Center Transit Center, St Louis Bus Station, and Chicago Bus Station in around 11h 26m.

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