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How to get fromSaint Charles to Mississippiby plane, bus (Greyhound), bus, train, or car

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There are 4 ways to get from Saint Charles to Mississippi by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Memphis (MEM)plane plane STL - MEM
    4h 59m
    $156–781

  2. Bus

    cheapest
    1. Take the bus from St Louis Bus Station to Jacksonbus bus Greyhound US1173
    13h 46m
    $84–164

  3. Bus, train

    1. Take the bus from St. Louis to Carbondalebus bus Amtrak Thruway Connecting Service
    2. Take the train from Carbondale to Jacksontrain train City of New Orleans
    14h 35m
    $159–344

  4. Drive 502.5 mi

    1. Drive from Saint Charles to Jacksoncar car 502.5 mi
    8h 9m
    $92–133

Saint Charles to Mississippi by bus and train

Calendar14Weekly Services
Duration13h 46mAverage Duration
Ticket$84Cheapest Price
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Questions & Answers

Map of how to get from Saint Charles to Mississippi.ExpandLaunch map view
  • Distance: 279.8 mi
  • Duration: 4h 59m

What companies run services between Saint Charles, MO, USA and Mississippi, USA?

Southwest Airlines, Delta, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Memphis (MEM) hourly. Alternatively, Greyhound-us operates a bus from St Louis Bus Station to Jackson once daily, and the journey takes 11h 45m. Greyhound USA also services this route once daily.

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