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How to get fromSaint Charles to Mississippiby plane, bus (Greyhound), bus, train, or car

Find Transport to Mississippi

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There are 5 ways to get from Saint Charles to Mississippi by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Memphis

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Memphis (MEM)plane plane STL - MEM
    6h
    $179–897

  2. Drive  502.5 mi

    cheapest
    1. Drive from Saint Charles to Jacksoncar car 502.5 mi
    8h 9m
    $89–129

  3. Bus (Greyhound)

    1. Take the bus from St Louis Bus Station to Jacksonbus bus Greyhound US1173
    14h 26m
    $105–158

  4. Bus, train

    1. Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus bus FlixBus N2521
    2. Take the train from Carbondale to Jacksontrain train City of New Orleans
    14h 31m
    $272–422

  5. Fly to Gulfport-Biloxi Regional Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Gulfport-Biloxi Regional Airport (GPT)plane plane STL - GPT
    6h 36m
    $123–534

Lambert–St. Louis International Airport (STL) to Memphis (MEM) flights

Calendar124Weekly Planes
Duration5h 13mAverage Duration
Ticket$142Cheapest Price
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Comparing Your Travel Options

Map of how to get from Saint Charles to Mississippi.ExpandLaunch map view
  • Distance: 284.2 mi
  • Duration: 6h

What companies run services between Saint Charles, MO, USA and Mississippi, USA?

Delta, Southwest Airlines, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Memphis (MEM) hourly. Alternatively, Greyhound USA operates a bus from St Louis Bus Station to Jackson twice daily. Tickets cost $90–140 and the journey takes 11h 45m.

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