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How to get fromSaint Charles to Myrtle Beachby plane, bus (Greyhound, Flixbus), or car

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There are 3 ways to get from Saint Charles to Myrtle Beach by plane, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR)plane plane STL - MYR
    3h 45m
    $100–458

  2. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus Greyhound US0186
    2. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus Greyhound US0641S
    23h 21m
    $154–304

  3. Drive 902.4 mi

    1. Drive from Saint Charles to Myrtle Beachcar car 902.4 mi
    15h 56m
    $165–238

Saint Charles to Myrtle Beach by bus and train

Calendar7Weekly Services
Duration23h 21mAverage Duration
Ticket$154Cheapest Price
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Questions & Answers

Map of how to get from Saint Charles to Myrtle Beach.ExpandLaunch map view
  • Distance: 745.8 mi
  • Duration: 3h 45m

What companies run services between Saint Charles, MO, USA and Myrtle Beach, SC, USA?

Southwest Airlines, Delta, and American Airlines fly from Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a bus from 4375 Rider Trail North Sb to Myrtle Beach Bus Station via North Hanley Transit Center, NORTH HANLEY station, CIVIC CENTER station, St Louis Bus Station, and Atlanta Bus Station in around 23h 21m.

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