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How to get fromSaint Charles to North Carolinaby plane, bus (Greyhound, Flixbus), or car

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There are 8 ways to get from Saint Charles to North Carolina by plane, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Charlotte Douglas International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Charlotte Douglas International Airport (CLT)plane plane STL - CLT
    4h 17m
    $127–707

  2. Fly to Fayetteville Municipal Airport

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Fayetteville Municipal Airport (FAY)plane plane STL - FAY
    6h 7m
    $115–523

  3. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus Greyhound US0186
    2. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus Greyhound US0670 / ...
    18h 29m
    $124–244

  4. Drive 730.6 mi

    1. Drive from Saint Charles to Charlottecar car 730.6 mi
    12h 29m
    $134–193

  5. Fly to Piedmont Triad International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Piedmont Triad International Airport (GSO)plane plane STL - GSO
    5h 52m
    $182–839

  6. Fly to Wilmington International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Wilmington International Airport (ILM)plane plane STL - ILM
    5h 55m
    $118–571

  7. Fly to Raleigh-Durham International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Raleigh-Durham International Airport (RDU)plane plane STL - RDU
    5h 1m
    $557–1,007

  8. Bus via 4375 Rider Trail North Sb

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus Greyhound US0186
    2. Take the bus from Atlanta Downtown to Charlotte Bus Stationbus bus FlixBus N2470
    19h
    $127–242

Saint Charles to North Carolina by bus and train

Calendar12Weekly Services
Duration18h 29mAverage Duration
Ticket$124Cheapest Price
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Questions & Answers

Map of how to get from Saint Charles to North Carolina.ExpandLaunch map view
  • Distance: 597.6 mi
  • Duration: 4h 17m

What companies run services between Saint Charles, MO, USA and North Carolina, USA?

American Airlines, Southwest Airlines, and Delta fly from Lambert–St. Louis International Airport (STL) to Charlotte Douglas International Airport (CLT) every 4 hours. Alternatively, you can take a bus from Riverport Lane @ Riverport Eb to Charlotte Bus Station via North Hanley Transit Center, NORTH HANLEY station, CIVIC CENTER station, St Louis Bus Station, and Atlanta Bus Station in around 18h 29m.

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