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How to get fromSaint Charles to Philadelphiaby plane, bus (Greyhound), train (Amtrak), car, or train

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There are 9 ways to get from Saint Charles to Philadelphia by plane, bus (Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Philadelphia International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Philadelphia International Airport (PHL)plane plane STL - PHL
    4h 40m
    $157–757
  2. Fly to John F. Kennedy International Airport, train

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to John F. Kennedy International Airport (JFK)plane plane STL - JFK
    2. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    6h 35m
    $128–1,063
  3. Bus (Greyhound)

    1. Take the bus from St Louis Bus Station to Philadelphia Bus Stationbus bus Greyhound US0421
    24h 6m
    $144–274
  4. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the train from Chicago Union Station to 30th Street Stationtrain train Cardinal
    33h 40m
    $434–894
  5. Drive 893.7 mi

    1. Drive from Saint Charles to Philadelphiacar car 893.7 mi
    15h 18m
    $164–236
  6. Fly to Baltimore-Washington International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Baltimore-Washington International Airport (BWI)plane plane STL - BWI
    2. Take the train from BWI Thurgood Marshall to 30th Street Stationtrain train
    6h 2m
    $148–1,306
  7. Fly to Laguardia Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Laguardia Airport (LGA)plane plane STL - LGA
    2. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    6h 28m
    $177–1,360
  8. Fly to Ronald Reagan Washington National Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Ronald Reagan Washington National Airport (DCA)plane plane STL - DCA
    2. Take the train from Washington Union Station to 30th Street Stationtrain train
    6h 7m
    $178–481
  9. Fly to Newark Liberty International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Newark Liberty International Airport (EWR)plane plane STL - EWR
    2. Take the train from Newark Liberty International Airport to 30th Street Stationtrain train
    6h 30m
    $380–1,059

Saint Charles to Philadelphia by bus and train (Greyhound)

Calendar21Weekly Services
Duration24h 6mAverage Duration
Ticket$144Cheapest Price
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Questions & Answers

What companies run services between Saint Charles, MO, USA and Philadelphia, PA, USA?

American Airlines, Southwest Airlines, and Delta fly from Lambert–St. Louis International Airport (STL) to Philadelphia International Airport (PHL) every 4 hours. Alternatively, Greyhound USA operates a bus from St Louis Bus Station to Philadelphia Bus Station 3 times a day. Tickets cost $140–270 and the journey takes 22h 5m.

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