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How to get fromSaint Charles to Tennesseeby bus, plane, bus (Greyhound, Flixbus), car, or bus (Amtrak, Flixbus)

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There are 6 ways to get from Saint Charles to Tennessee by bus, plane, bus (Greyhound, Flixbus), car, or bus (Amtrak, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 34 bus, fly to Nashville

    best
    1. Take the bus from 4375 Rider Trail North Sb to North Hanley Transit Centerbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Nashville (BNA)plane plane STL - BNA
    3h 42m
    $146–756

  2. Bus via Carbondale

    cheapest
    1. Take the bus from St. Louis to Carbondalebus bus Amtrak Thruway Connecting Service
    2. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus FlixBus N2521
    8h 44m
    $48–89

  3. Bus

    1. Take the bus from St Louis Bus Station to Nashville Bus Stationbus bus Greyhound US0186 / ...
    8h 36m
    $49–84

  4. Drive  328.3 mi

    1. Drive from Saint Charles to Nashvillecar car 328.3 mi
    5h 26m
    $60–87

  5. Fly to Mcghee Tyson Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS)plane plane STL - TYS
    5h 16m
    $199–974

  6. Fly to Chattanooga Metropolitan Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Chattanooga Metropolitan Airport (CHA)plane plane STL - CHA
    5h 31m
    $95–463

Saint Charles to Tennessee by bus and train

Calendar19Weekly Services
Duration8h 36mAverage Duration
Ticket$49Cheapest Price
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Comparing Your Travel Options

Map of how to get from Saint Charles to Tennessee.ExpandLaunch map view
  • Distance: 298.5 mi
  • Duration: 3h 42m

What companies run services between Saint Charles, MO, USA and Tennessee, USA?

Greyhound USA operates a bus from St Louis Bus Station to Nashville Bus Station twice daily. Tickets cost $50–80 and the journey takes 6h 35m. Flixbus USA also services this route 5 times a week. Alternatively, Southwest Airlines, Delta, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS) hourly.

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