There are 7 ways to get from Saint George Island to Florida Keys by car, plane, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive 645.1 mi
best- Drive from Saint George Island to Florida Keyscar 645.1 mi
12h 47m$118–171Drive to Tallahassee, fly to Key West International Airport
- Drive from Saint George Island to Tallahassee (TLH)car
- Fly from Tallahassee (TLH) to Key West International Airport (EYW)plane TLH - EYW
8h 1m$146–444Drive to Tallahassee, fly to Miami International Airport, shuttle
- Drive from Saint George Island to Tallahassee (TLH)car
- Fly from Tallahassee (TLH) to Miami International Airport (MIA)plane TLH - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
8h 42m$226–564Drive to Tallahassee, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Drive from Saint George Island to Tallahassee (TLH)car
- Fly from Tallahassee (TLH) to Fort Lauderdale–Hollywood International Airport (FLL)plane TLH - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
9h 14m$396–1,074Drive to Tampa, fly to Key West International Airport
- Drive from Saint George Island to Tampa-Airport-TPAcar
- Fly from Tampa (TPA) to Key West International Airport (EYW)plane TPA - EYW
9h 56m$200–561Drive to Destin–Fort Walton Beach Airport, fly to Miami International Airport, shuttle
- Drive from Saint George Island to Destin–Fort Walton Beach Airport (VPS)car
- Fly from Destin–Fort Walton Beach Airport (VPS) to Miami International Airport (MIA)plane VPS - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
10h 29m$238–561Drive to Saint Petersburg–Clearwater International Airport, fly to Key West International Airport
- Drive from Saint George Island to Saint Petersburg–Clearwater International Airport (PIE)car
- Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane PIE - EYW
9h 54m$166–411
Tallahassee (TLH) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Saint George Island to Florida Keys is to drive which costs $110 - $170 and takes 12h 47m.
The fastest way to get from Saint George Island to Florida Keys is to drive and fly which takes 8h 1m and costs $140 - $450.
The distance between Saint George Island and Florida Keys is 649 miles. The road distance is 648.8 miles.
It takes approximately 12h 47m to drive 648.8 miles from Saint George Island to Florida Keys.
Yes, the driving distance between Saint George Island to Florida Keys is 649 miles. It takes approximately 12h 47m to drive from Saint George Island to Florida Keys.
There are 967+ hotels available in Florida Keys.
What companies run services between Saint George Island, FL, USA and Florida Keys, FL, USA?
You can drive from Saint George Island to Florida Keys in around 12h 47m.
- Website
- aa.com
Flights from Tallahassee to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 31m
- When
- Every day
- Estimated price
- $55–330
Flights from Tallahassee to Key West International Airport via Charlotte
- Ave. Duration
- 6h 26m
- When
- Every day
- Estimated price
- $95–440
Flights from Tallahassee to Miami International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $60–360
Flights from Destin–Fort Walton Beach Airport to Miami International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $60–340
- Website
- flybreeze.com
Flights from Tallahassee to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 28m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $210–850
Flights from Tampa to Key West International Airport
- Ave. Duration
- 1h 18m
- When
- Thursday, Sunday, Monday, Wednesday, Friday, and Tuesday
- Estimated price
- $70–390
- Website
- delta.com
Flights from Tallahassee to Key West International Airport via Atlanta
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $80–390
- Website
- allegiantair.com
Flights from Saint Petersburg–Clearwater International Airport to Key West International Airport
- Ave. Duration
- 1h 4m
- When
- Monday, Friday, Wednesday, Saturday, Thursday, and Sunday
- Estimated price
- $35–240
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- https://www.keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- https://www.keysshuttle.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide

