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How to get fromSaint James City to Key Westby taxi, ferry, bus (Flixbus, Greyhound), car, plane, or bus

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There are 5 ways to get from Saint James City to Key West by taxi, ferry, bus (Flixbus, Greyhound), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, ferry

    best
    1. Take the taxi from Saint James City to Fort Myers Beach, FLtaxi taxi
    2. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry Fort Myers Beach
    4h 57m
    $230–248

  2. Drive  299 mi

    cheapest
    1. Drive from Saint James City to Key Westcar car 299 mi
    6h 35m
    $55–79

  3. Bus

    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus
    3. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    12h 33m
    $120–164

  4. Taxi to Ft. Myers, fly

    1. Take the taxi from Saint James City to Ft-Myers-Airport-RSWtaxi taxi
    2. Fly from Ft. Myers (RSW) to Key West International Airport (EYW)plane plane RSW - EYW
    5h 27m
    $221–599

  5. Taxi, bus to Miami International Airport, fly

    1. Take the taxi from Saint James City to Fort Myers 7-11taxi taxi
    2. Take the bus from Fort Myers 7-11 to Miami Airportbus bus
    3. Fly from Miami International Airport (MIA) to Key West International Airport (EYW)plane plane MIA - EYW
    5h 45m
    $164–388

Ft. Myers (RSW) to Key West International Airport (EYW) flights

Calendar35Weekly Planes
Duration5h 22mAverage Duration
Ticket$95Cheapest Price
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Comparing Your Travel Options

Map of how to get from Saint James City to Key West.ExpandLaunch map view
  • Distance: 171.7 mi
  • Duration: 4h 57m

What companies run services between Saint James City, FL, USA and Key West, FL, USA?

You can take a vehicle from Saint James City to N Roosevelt & 3rd Street via Cape Coral Transfer Center, Fort Myers Bus Stop, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 12h 33m.

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