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How to get fromSaint Joseph to Knoxvilleby train, plane, bus, bus (Amtrak, Flixbus), or car

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There are 9 ways to get from Saint Joseph to Knoxville by train, plane, bus, bus (Amtrak, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago O'Hare International Airport, fly to Mcghee Tyson Airport

    best
    1. Take the train from St. Joseph-Benton Harbor Station to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS)plane plane ORD - TYS
    6h 4m
    $194–782

  2. Drive 518.6 mi

    cheapest
    1. Drive from Saint Joseph to Knoxvillecar car 518.6 mi
    9h 11m
    $95–137

  3. Train, bus

    1. Take the train from St. Joseph-Benton Harbor Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    36h 43m
    $500–960

  4. Bus

    1. Take the bus from St. Joseph-Benton Harbor Station to Chicago Union Stationbus bus
    2. Take the bus from Chicago Bus Station to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    40h 52m
    $281–409

  5. Train to Chicago Midway International Airport, fly to Mcghee Tyson Airport

    1. Take the train from St. Joseph-Benton Harbor Station to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Mcghee Tyson Airport (TYS)plane plane MDW - TYS
    5h 35m
    $217–935

  6. Bus to Kalamazoo-Battle Creek International Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Benton Harbor Bus Stop to Kalamazoo Bus Stopbus bus
    2. Fly from Kalamazoo-Battle Creek International Airport (AZO) to Mcghee Tyson Airport (TYS)plane plane AZO - TYS
    8h 17m
    $202–814

  7. Train to Chicago O'Hare International Airport, fly to Asheville Regional Airport, drive

    1. Take the train from St. Joseph-Benton Harbor Station to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    8h 7m
    $111–437

  8. Train to Chicago Midway International Airport, fly to Nashville, drive

    1. Take the train from St. Joseph-Benton Harbor Station to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Nashville (BNA)plane plane MDW - BNA
    3. Drive from Nashville-Airport-BNA to Knoxvillecar car
    8h 5m
    $127–535

  9. Train, bus via Ossining

    1. Take the train from St. Joseph-Benton Harbor Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    3. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    37h 20m
    $455–837

Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS) flights

Calendar74Weekly Planes
Duration2h 46mAverage Duration
Ticket$109Cheapest Price
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Questions & Answers

Map of how to get from Saint Joseph to Knoxville.ExpandLaunch map view
  • Distance: 595.7 mi
  • Duration: 6h 4m

What companies run services between Saint Joseph, MI, USA and Knoxville, TN, USA?

You can take a bus from St. Joseph-Benton Harbor Station to Knoxville Station Hall of Fame via Chicago Union Station, Chicago Bus Station, New York, NY, Knoxville, TN, Walmart, and Charlie Haun WB Aft Washington PK in around 40h 52m.

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