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How to get fromSaint Joseph to Mayo Clinicby train, plane, bus (Amtrak), bus, car, or bus (Amtrak, Flixbus, Greyhound)

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There are 9 ways to get from Saint Joseph to Mayo Clinic by train, plane, bus (Amtrak), bus, car, or bus (Amtrak, Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago O'Hare International Airport, fly to Rochester

    best
    1. Take the train from St. Joseph-Benton Harbor Station to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane plane ORD - RST
    6h 41m
    $70–392

  2. Bus

    1. Take the bus from St. Joseph-Benton Harbor Station to Chicago Union Stationbus bus
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    12h 4m
    $107–174

  3. Train, bus

    1. Take the train from St. Joseph-Benton Harbor Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochesterbus bus
    13h 2m
    $175–367

  4. Drive 441.6 mi

    1. Drive from Saint Joseph to Mayo Cliniccar car 441.6 mi
    7h 26m
    $81–117

  5. Train to Chicago O'Hare International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from St. Joseph-Benton Harbor Station to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Minneapolis–Saint Paul International Airport (MSP)plane plane ORD - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 24m
    $301–564

  6. Train to Chicago Midway International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from St. Joseph-Benton Harbor Station to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Minneapolis–Saint Paul International Airport (MSP)plane plane MDW - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 14m
    $154–567

  7. Train to Gerald R. Ford International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from St. Joseph-Benton Harbor Station to Grand Rapids Vernon J. Ehlers Stationtrain train
    2. Fly from Gerald R. Ford International Airport (GRR) to Minneapolis–Saint Paul International Airport (MSP)plane plane GRR - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 40m
    $168–662

  8. Train, bus via Madison

    1. Take the train from St. Joseph-Benton Harbor Station to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    12h 4m
    $102–187

  9. Bus via Chicago

    1. Take the bus from St. Joseph-Benton Harbor Station to Chicago Union Stationbus bus
    2. Take the bus from Chicago Bus Station to Madisonbus bus
    3. Take the bus from Madison to Rochesterbus bus
    12h 20m
    $107–169

Saint Joseph to Mayo Clinic by bus and foot

Calendar1Weekly Services
Duration12h 4mAverage Duration
Ticket$107Cheapest Price
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Questions & Answers

Map of how to get from Saint Joseph to Mayo Clinic.ExpandLaunch map view
  • Distance: 384.6 mi
  • Duration: 6h 41m

What companies run services between Saint Joseph, MI, USA and Mayo Clinic, MN, USA?

You can take a bus from St. Joseph-Benton Harbor Station to Mayo Clinic via Chicago Union Station, W Jackson Blvd, after S Clinton St, 250 N. Lake St - Madison UW Campus, Madison, and Rochester in around 12h 4m.

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