There are 4 ways to get from Saint Joseph to Mayo Clinic by bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from St. Joseph to Kansas Citybus
- Take the bus from Kansas City to Albert Leabus
- Take the bus from Albert Lea to Rochesterbus
11h 23mDrive 382.7 mi
cheapest- Drive from Saint Joseph to Mayo Cliniccar 382.7 mi
6h 26m$70–101Bus, fly to Rochester
- Take the bus from St. Joseph to Kansas Citybus
- Fly from Kansas City (MCI) to Rochester (RST)plane MCI - RST
8h 42m$104–503Bus, fly to Minneapolis–Saint Paul International Airport
- Take the bus from St. Joseph to Kansas Citybus
- Fly from Kansas City (MCI) to Minneapolis–Saint Paul International Airport (MSP)plane MCI - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
8h 6m$676–1,035
Kansas City (MCI) to Rochester (RST) flights
Questions & Answers
The cheapest way to get from Saint Joseph to Mayo Clinic is to drive which costs $70 - $110 and takes 6h 26m.
The fastest way to get from Saint Joseph to Mayo Clinic is to drive which takes 6h 26m and costs $70 - $110.
No, there is no direct bus from Saint Joseph to Mayo Clinic. However, there are services departing from St. Joseph and arriving at Rochester via Kansas City and Albert Lea. The journey, including transfers, takes approximately 11h 23m.
The distance between Saint Joseph and Mayo Clinic is 468 miles. The road distance is 385 miles.
The best way to get from Saint Joseph to Mayo Clinic without a car is to bus which takes 11h 23m and costs .
It takes approximately 11h 23m to get from Saint Joseph to Mayo Clinic, including transfers.
Saint Joseph to Mayo Clinic bus services, operated by Jefferson Lines, depart from St. Joseph station.
Saint Joseph to Mayo Clinic bus services, operated by Jefferson Lines, arrive at Kansas City station.
Yes, the driving distance between Saint Joseph to Mayo Clinic is 385 miles. It takes approximately 6h 26m to drive from Saint Joseph to Mayo Clinic.
There are 75+ hotels available in Mayo Clinic.
What companies run services between Saint Joseph, MO, USA and Mayo Clinic, MN, USA?
You can take a bus from St. Joseph to Mayo Clinic via Kansas City, Albert Lea, and Rochester in around 11h 23m.
- Website
- delta.com
Flights from Kansas City to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $80–470
Flights from Kansas City to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $90–550
- Website
- aa.com
Flights from Kansas City to Rochester via Chicago O'Hare
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $100–550
- Website
- united.com
Flights from Kansas City to Rochester via Chicago O'Hare
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $100–550
- Website
- southwest.com
Flights from Kansas City to Minneapolis–Saint Paul International Airport via Chicago Midway
- Ave. Duration
- 3h 50m
- When
- Saturday
- Estimated price
- $130–700
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from St. Joseph to Kansas City
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $23–35
- Book at
- https://www.jeffersonlines.com
- Adult
- $23–35
Bus from Kansas City to Albert Lea
- Ave. Duration
- 6h 45m
- Frequency
- 3 times a day
- Estimated price
- $80–120
- Book at
- https://www.jeffersonlines.com
- Adult
- $80–120
Bus from St. Joseph to Kansas City
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $23–35
- Book at
- https://www.jeffersonlines.com
- Adult
- $23–35
Bus from St. Joseph to Kansas City
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $23–35
- Book at
- https://www.jeffersonlines.com
- Adult
- $23–35
- Website
- example.com
Bus from Albert Lea to Rochester
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Schedules at
- example.com
- Phone
- + 1 507-280-9270
- Website
- groometransportation.com
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
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