There are 5 ways to get from Saint Louis County to Chicago by bus, plane, train (Amtrak), bus (Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Line 98 bus, fly to Chicago Midway International Airport
best- Take the bus from New Ballas @ Ronyn Park Nb to North Hanley Transit Centerbus
- Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane STL - MDW
3h 37m$61–379Bus (Flixbus)
cheapest- Take the bus from St Louis Bus Station to Chicago Bus Stationbus FlixBus N2521 / ...
8h 52m$52–87Train (Amtrak)
- Take the train from St. Louis to Chicago Union Stationtrain Lincoln Service / ...
6h 44m$89–194Drive 306.4 mi
- Drive from Saint Louis County to Chicagocar 306.4 mi
5h 19m$56–81Line 98 bus, fly to Chicago O'Hare International Airport
- Take the bus from New Ballas @ Ronyn Park Nb to North Hanley Transit Centerbus
- Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane STL - ORD
4h$276–709
Saint Louis County to Chicago by bus and train (Amtrak)
Questions & Answers
The cheapest way to get from Saint Louis County to Chicago is to bus which costs $50 - $90 and takes 8h 52m.
The fastest way to get from Saint Louis County to Chicago is to line 98 bus and fly which takes 3h 37m and costs $60 - $380.
No, there is no direct bus from Saint Louis County to Chicago station. However, there are services departing from Ballas Transit Center and arriving at Chicago Bus Station via Clayton Transit Center and St Louis Bus Station. The journey, including transfers, takes approximately 8h 52m.
No, there is no direct train from Saint Louis County station to Chicago station. However, there are services departing from CLAYTON station and arriving at Chicago Union Station via St. Louis. The journey, including transfers, takes approximately 6h 44m.
The distance between Saint Louis County and Chicago is 283 miles. The road distance is 308.2 miles.
The best way to get from Saint Louis County to Chicago without a car is to train which takes 6h 44m and costs $85 - $200.
It takes approximately 3h 37m to get from Saint Louis County to Chicago, including transfers.
Saint Louis County to Chicago bus services, operated by Flixbus USA, depart from St Louis Bus Station.
Saint Louis County to Chicago train services, operated by Amtrak, depart from St. Louis station.
The best way to get from Saint Louis County to Chicago is to train which takes 6h 44m and costs $85 - $200. Alternatively, you can bus, which costs $50 - $90 and takes 8h 52m.
What companies run services between Saint Louis County, MO, USA and Chicago, IL, USA?
Amtrak operates a train from St. Louis to Chicago Union Station 5 times a day. Tickets cost $85–190 and the journey takes 4h 55m. Alternatively, Flixbus USA operates a bus from St Louis Bus Station to Chicago Bus Station 4 times a day. Tickets cost $50–85 and the journey takes 6h 5m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $55–370
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $45–310
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $45–310
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $85–190
- Website
- Amtrak
- Phone
- 314-982-1406
- [email protected]
- Website
- Metro St Louis
Bus from New Ballas @ Ronyn Park Nb to North Hanley Transit Center
- Ave. Duration
- 32 min
- Frequency
- Hourly
- Estimated price
- $1
- Website
- Metro St Louis
Bus from New Ballas @ Ronyn Park Nb to North Hanley Transit Center
- Ave. Duration
- 32 min
- Frequency
- Hourly
- Estimated price
- $1
- Website
- Metro St Louis
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Chicago Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- 4 times a day
- Estimated price
- $50–85
- Schedules at
- Flixbus USA
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More Questions & Answers
Saint Louis County to Chicago bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
Saint Louis County to Chicago train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Saint Louis County to Chicago is 308 miles. It takes approximately 5h 19m to drive from Saint Louis County to Chicago.
There are 1293+ hotels available in Chicago.