There are 3 ways to get from Saint Louis County to Des Moines by plane, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM)plane STL - DSM
5h 22m$151–825Drive 318.2 mi
cheapest- Drive from Saint Louis County to Des Moinescar 318.2 mi
6h 20m$59–84Bus (Greyhound)
- Take the bus from St Louis Bus Station to Des Moinesbus Greyhound US0153S
10h 22m$64–124
Saint Louis County to Des Moines by bus and train (Greyhound)
Questions & Answers
The cheapest way to get from Saint Louis County to Des Moines is to drive which costs $55 - $85 and takes 6h 20m.
The fastest way to get from Saint Louis County to Des Moines is to fly which takes 5h 22m and costs $150 - $850.
No, there is no direct bus from Saint Louis County to Des Moines. However, there are services departing from Missouri Baptist Hospital Loop and arriving at Des Moines via St Louis Bus Station. The journey, including transfers, takes approximately 10h 22m.
The distance between Saint Louis County and Des Moines is 286 miles. The road distance is 320.1 miles.
The best way to get from Saint Louis County to Des Moines without a car is to bus which takes 10h 22m and costs $60 - $130.
It takes approximately 5h 22m to get from Saint Louis County to Des Moines, including transfers.
Saint Louis County to Des Moines bus services, operated by Greyhound USA, depart from St Louis Bus Station.
The best way to get from Saint Louis County to Des Moines is to fly which takes 5h 22m and costs $150 - $850. Alternatively, you can bus, which costs $60 - $130 and takes 10h 22m.
Saint Louis County to Des Moines bus services, operated by Greyhound USA, arrive at Des Moines station.
Yes, the driving distance between Saint Louis County to Des Moines is 320 miles. It takes approximately 6h 20m to drive from Saint Louis County to Des Moines.
What companies run services between Saint Louis County, MO, USA and Des Moines, IA, USA?
Southwest Airlines, American Airlines, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM) hourly. Alternatively, Greyhound USA operates a bus from St Louis Bus Station to Des Moines once daily. Tickets cost $60–120 and the journey takes 8h 30m.
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Des Moines via Minneapolis
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $150–850
Flights from Lambert–St. Louis International Airport to Des Moines via Atlanta
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $230–1,100
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 4h 16m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $130–800
Flights from Lambert–St. Louis International Airport to Des Moines via Denver
- Ave. Duration
- 5h 15m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $240–1,100
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $130–800
Flights from Lambert–St. Louis International Airport to Des Moines via Denver
- Ave. Duration
- 5h 42m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $240–1,100
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $130–800
Flights from Lambert–St. Louis International Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $220–1,100
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Des Moines
- Ave. Duration
- 8h 30m
- Frequency
- Once daily
- Estimated price
- $60–120
- Website
- Greyhound
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