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How to get fromSaint Louis County to Detroitby bus, plane, train (Amtrak), bus (Greyhound), car, or bus (Flixbus)

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There are 5 ways to get from Saint Louis County to Detroit by bus, plane, train (Amtrak), bus (Greyhound), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 98 bus, fly

    best
    1. Take the bus from New Ballas @ Ronyn Park Nb to North Hanley Transit Centerbus bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Detroit (DTW)plane plane STL - DTW
    4h 44m
    $456–956

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Detroit Bus Stationbus bus Greyhound US0112
    13h 50m
    $77–152

  3. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the train from Chicago Union Station to Detroittrain train Wolverine
    13h 4m
    $174–384

  4. Drive 531.6 mi

    1. Drive from Saint Louis County to Detroitcar car 531.6 mi
    9h 8m
    $97–141

  5. Bus via Auburn Gresham (Flixbus)

    1. Take the bus from St Louis Bus Station to Chicagobus bus FlixBus N2521
    2. Take the bus from Chicago to Detroit Bus Stationbus bus FlixBus 2552
    16h 6m
    $99–179

Saint Louis County to Detroit by bus and train (Amtrak)

Calendar21Weekly Services
Duration13h 4mAverage Duration
Ticket$174Cheapest Price
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Questions & Answers

Map of how to get from Saint Louis County to Detroit.ExpandLaunch map view
  • Distance: 480.2 mi
  • Duration: 4h 44m

What companies run services between Saint Louis County, MO, USA and Detroit, MI, USA?

You can take a bus from Clayton @ Devondale Eb to Detroit via Clayton Transit Center, CLAYTON station, CIVIC CENTER station, St. Louis, and Chicago Union Station in around 13h 4m. Alternatively, you can take a bus from New Ballas @ Ronyn Park Nb to Detroit Bus Station via North Hanley Transit Center, Civic Center Transit Center, St Louis Bus Station, and Indianapolis Union Station in around 13h 50m.

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